Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
Investigation of Magnesium Incorporation Within Gelatin/Calcium Phosphate Nanocomposite Scaffold for Bone Tissue Engineering Publisher



Baheiraei N1 ; Azami M1 ; Hosseinkhani H2
Authors

Source: International Journal of Applied Ceramic Technology Published:2015


Abstract

In this study, diffusional method was used to prepare a calcium phosphate/gelatin nanocomposite as a scaffold for bone tissue repair. Incorporation of magnesium (Mg) into mineral phase of the scaffold was also investigated. Addition of Mg ions to the synthesis process caused formation of magnesium phosphate (MgP) and hydroxyapatite (HAp). However, analyses data for the sample lacking Mg showed that the mineral formed within GEL had a low crystalline nature, consisting of HAp and octacalcium phosphate (OCP). With addition of Mg within the structure of precipitated minerals, morphology of minerals was dramatically changed toward being irregular and less ordered. © 2013 The American Ceramic Society.
Related Docs
View other Related Docs
1. Synergistic Effects of Carbohydrate Polymers on the Performance of Hybrid Injectable Bone Pastes, European Polymer Journal (2019)
2. Bone Reconstruction in Rat Calvarial Defects by Chitosan/Hydroxyapatite Nanoparticles Scaffold Loaded With Unrestricted Somatic Stem Cells, Artificial Cells# Nanomedicine and Biotechnology (2015)
3. Incorporation of Nanoalumina Improves Mechanical Properties and Osteogenesis of Hydroxyapatite Bioceramics, ACS Biomaterials Science and Engineering (2018)
Experts (# of related papers)
View all Related Experts
Mahmoud Azami (5)
Nasrin Lotfibakhshaiesh (2)
Other Related Docs
4. Efficacy of the Biomaterials 3 Wt%-Nanostrontium-Hydroxyapatite-Enhanced Calcium Phosphate Cement (Nanosr-Cpc) and Nanosr-Cpc-Incorporated Simvastatin-Loaded Poly(Lactic-Co-Glycolic-Acid) Microspheres in Osteogenesis Improvement: An Explorative Multi-Phase Experimental in Vitro/Vivo Study, Materials Science and Engineering C (2016)
5. A Comparative Study of 3D-Printed Scaffolds Fabricated From Different Hydroxyapatite Sources for Bone Tissue Engineering Applications, Advanced Composite Materials (2024)
6. Zirconium Modified Calcium-Silicate-Based Nanoceramics: An in Vivo Evaluation in a Rabbit Tibial Defect Model, International Journal of Applied Ceramic Technology (2019)
7. Multifunctional Gelatin–Tricalcium Phosphate Porous Nanocomposite Scaffolds for Tissue Engineering and Local Drug Delivery: In Vitro and in Vivo Studies, Journal of the Taiwan Institute of Chemical Engineers (2019)
8. Magnesium Oxide Nanoparticle Reinforced Pumpkin-Derived Nanostructured Cellulose Scaffold for Enhanced Bone Regeneration, International Journal of Biological Macromolecules (2024)
9. Bioactive Glass Modified Calcium Phosphate Cement With Improved Bioactive Properties: A Potential Material for Dental Pulp-Capping Approaches, Journal of Biomimetics# Biomaterials and Biomedical Engineering (2021)
10. Preparation and in Vitro Osteogenic Evaluation of Biomimetic Hybrid Nanocomposite Scaffolds Based on Gelatin/Plasma Rich in Growth Factors (Prgf) and Lithium-Doped 45S5 Bioactive Glass Nanoparticles, Journal of Polymers and the Environment (2023)
11. Preparation and Characterization of Highly Porous Ceramic-Based Nanocomposite Scaffolds With Improved Mechanical Properties Using the Liquid Phase-Assisted Sintering Method, Proceedings of the Institution of Mechanical Engineers# Part L: Journal of Materials: Design and Applications (2019)
12. Scalable and Cost-Effective Generation of Osteogenic Micro-Tissues Through the Incorporation of Inorganic Microparticles Within Mesenchymal Stem Cell Spheroids, Biofabrication (2020)
13. Incorporation of Calcium Phosphate Cement Into Decellularized Extracellular Matrix Enhances Its Bone Regenerative Properties, Colloids and Surfaces B: Biointerfaces (2024)
14. Effects of the Biological Environment on Ceramics: Degradation, Cell Response, and in Vivo Behavior, Fundamental Biomaterials: Ceramics (2018)
15. In Vitro and in Vivo Investigation of Poly(Lactic Acid)/Hydroxyapatite Nanoparticle Scaffold Containing Nandrolone Decanoate for the Regeneration of Critical-Sized Bone Defects, Nanomedicine Journal (2020)
16. Carboxymethyl Chitosan/Gelatin/Hydroxyapatite Biomimetic Cryogels for Bone Regeneration, Bioinspired# Biomimetic and Nanobiomaterials (2023)
17. Fabrication of Cancellous Biomimetic Chitosan-Based Nanocomposite Scaffolds Applying a Combinational Method for Bone Tissue Engineering, Journal of Biomedical Materials Research - Part A (2015)
18. Silk Fibroin/Hydroxyapatite Composites for Bone Tissue Engineering, Biotechnology Advances (2018)
19. Effect of Addition of Titanium on Structural, Mechanical and Biological Properties of 45S5 Glass-Ceramic, Ceramics International (2018)
20. A 3D-Printed Bone Scaffold of Carboxymethyl Chitosan/Gelatin/Akermanite: Synthesis and Evaluation, Journal of Polymers and the Environment (2025)