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Are Itch and Scratching the Nausea and Vomiting of Skin? Publisher Pubmed



Ostadhadi S1, 2, 4 ; Azimi E3 ; Lerner EA3 ; Dehpour AR1, 2, 4
Authors

Source: Experimental Dermatology Published:2016


Abstract

The physiologic similarities between itch and nausea may not be evident initially, but they share the role of repelling irritants and toxins from the body by inducting scratching and vomiting, respectively. In addition, itch and nausea frequently occur together in certain conditions such as uraemia. Here we show that the mechanisms underlying itch and nausea overlap and that advances in either field may influence the identification of novel drug targets, particularly for itch. © 2016 John Wiley & Sons A/S.
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