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Synthesis, Reaction and Biological Activity of Pyrazolo[5,1-C][1,2,4]Benzotriazine 5-Oxides Publisher



Ziarani GM1 ; Mostofi M1 ; Lashgari N1 ; Mahdavi M2
Authors

Source: Politics and Religion Journal Published:2018


Abstract

[1,2,4]Benzotriazine fused to pyrazole ring is a privileged heterocyclic scaffold present in numerous pharmacologically active compounds. Till date, various pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxides and their deoxy analogues, possessing a broad spectrum of potent pharmacological activities, have been reported. In this review, we highlighted synthesis, chemical reactions, medicinal chemistry aspects and applications of fused pyrazole derivatives of [1,2,4]benzotriazine analogues reported so far. © 2018 The Japan Institute of Heterocyclic Chemistry Received.
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