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Hope on the Horizon? Aptamers in Diagnosis of Invasive Fungal Infections Publisher Pubmed



Khodavaisy S1, 2 ; Xu J1
Authors

Source: Genes Published:2024


Abstract

Despite remarkable advances in the diagnosis of invasive fungal infections (IFIs), rapid, specific, sensitive, and cost-effective detection methods remain elusive. Due to their stability, ease of production, and specificity to signature molecules of fungal pathogens, short single-stranded sequences of DNA, RNA, and XNA, collectively called aptamers, have emerged as promising diagnostic markers. In this perspective, we summarize recent progress in aptamer-based diagnostic tools for IFIs and discuss how these tools could potentially meet the needs and provide economical and simple solutions for point-of-care for better management of IFIs. © 2024 by the authors.
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