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Introduction to the Neuroimmunology of Multiple Sclerosis Publisher



Yazdanpanah N1, 2, 3 ; Rezaei N2, 3, 4
Authors

Source: Translational Neuroimmunology: Multiple Sclerosis: Volume 8 Published:2023


Abstract

Multiple sclerosis (MS), known as the most common demyelinating disease in high-income regions, is a chronic disabling disease with an autoimmune pathology, mainly affecting the central nervous system (CNS). In 1868, for the first time, Jean-Martin Charcot described the features of MS as la sclerose en plaques. MS physiopathology is a complex picture of interactions between various environmental and genetic factors. Therefore, it is necessary to reap the benefits of interdisciplinary approaches both in basic science studies and in the clinic. Translational research is of utmost importance in complex diseases like MS to help apply preclinical and laboratory findings in clinical practice. © 2023 Elsevier Inc. All rights reserved.
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