Computational Approaches for Toxicology and Pharmacokinetic Properties Prediction

Computational Approaches for Toxicology and Pharmacokinetic Properties Prediction Publisher Pubmed

Kaboudi N ; Shekari T ; Shayanfar A ; Pimentel AS

Source: Journal of Pharmacokinetics and Pharmacodynamics Published:2025

Abstract

Pharmacokinetics and toxicological studies how the body reacts to a specific administered substance, such as a drug, toxin, or food. Each substance experiences these four steps: absorption, distribution, metabolism, and excretion, which are the main parameters in pharmacokinetics studies. Many toxic endpoints exist. There are three main ways to measure toxicology and pharmacokinetic parameters: in vivo, in vitro, and in-silico. Knowing toxicological and pharmacokinetic parameters before developing a new drug candidate could save time and resources, as clinical studies are highly cost-demanding. This review aims to gather studies using in-silico methodologies to predict pharmacokinetic properties. © 2025 Elsevier B.V., All rights reserved.

Style	Citing Format
MLA	Kaboudi N, et al.. "Computational Approaches for Toxicology and Pharmacokinetic Properties Prediction." Journal of Pharmacokinetics and Pharmacodynamics, vol. 52, no. 5, 2025, pp. -.
APA	Kaboudi N, Shekari T, Shayanfar A, Pimentel AS (2025). Computational Approaches for Toxicology and Pharmacokinetic Properties Prediction. Journal of Pharmacokinetics and Pharmacodynamics, 52(5), -.
Chicago	Kaboudi N, Shekari T, Shayanfar A, Pimentel AS. "Computational Approaches for Toxicology and Pharmacokinetic Properties Prediction." Journal of Pharmacokinetics and Pharmacodynamics 52, no. 5 (2025): -.
Harvard	Kaboudi N et al. (2025) 'Computational Approaches for Toxicology and Pharmacokinetic Properties Prediction', Journal of Pharmacokinetics and Pharmacodynamics, 52(5), pp. -.
Vancouver	Kaboudi N, Shekari T, Shayanfar A, Pimentel AS. Computational Approaches for Toxicology and Pharmacokinetic Properties Prediction. Journal of Pharmacokinetics and Pharmacodynamics. 2025;52(5):-.
BibTex	@article{ author = {Kaboudi N and Shekari T and Shayanfar A and Pimentel AS}, title = {Computational Approaches for Toxicology and Pharmacokinetic Properties Prediction}, journal = {Journal of Pharmacokinetics and Pharmacodynamics}, volume = {52}, number = {5}, pages = {-}, year = {2025} }
RIS	TY - JOUR AU - Kaboudi N AU - Shekari T AU - Shayanfar A AU - Pimentel AS TI - Computational Approaches for Toxicology and Pharmacokinetic Properties Prediction JO - Journal of Pharmacokinetics and Pharmacodynamics VL - 52 IS - 5 SP - EP - PY - 2025 ER -

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