Gorham–Stout Syndrome, the Challenge in Diagnosis and Unique in Treatment: A Case Report Publisher Pubmed



Saberi S¹ ; Bagheri N¹ ; Kalantar SH¹ ; Saffar H² ; Khabiri SS¹
Source: Journal of Medical Case Reports Published:2023

Abstract

Background: Gorham–Stout disease is a rare condition with fewer than 400 reported cases in the literature. The presentation of Gorham–Stout disease varies on the basis of location, extent, fracture, and accompanying symptoms. It lacks a specific histopathological appearance but is characterized by vascular changes and the absence of cellular atypia. Case presentation: This article presents a case study of a 16-year-old Persian boy with an entire femur with Gorham–Stout disease, highlighting the difficulties in managing this condition. The lack of a clear diagnosis resulted in prolonged procedures, delayed medical treatments, and ultimately required total femoral replacement with an endoprosthesis. Conclusion: It is important to note that raising awareness of this disease and its potential complications can facilitate timely and appropriate treatment for patients presenting in the early stages of the disease. © 2023, BioMed Central Ltd., part of Springer Nature.