Graphene/Cobalt Nanocarrier for Hyperthermia Therapy and Mri Diagnosis

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):

Share By

Graphene/Cobalt Nanocarrier for Hyperthermia Therapy and Mri Diagnosis Publisher Pubmed

Hatamie S¹ ; Ahadian MM¹ ; Ghiass MA¹ ; Iraji Zad A^{1, 2} ; Saber R^{3, 4} ; Parseh B⁵ ; Oghabian MA⁵ ; Shanehsazzadeh Zadeh S⁵

Source: Colloids and Surfaces B: Biointerfaces Published:2016

Abstract

Graphene/cobalt nanocomposites are promising materials for theranostic nanomedicine applications, which are defined as the ability to diagnose, provide targeted therapy and monitor the response to the therapy. In this study, the composites were synthesized via chemical method, using graphene oxide as the source material and assembling cobalt nanoparticles of 15 nm over the surface of graphene sheets. Various characterization techniques were then employed to reveal the morphology, size and structure of the nanocomposites, such as X-ray diffraction analysis, X-ray photoelectron spectroscopy, Fourier transform infrared spectroscopy, high resolution transmission electron microscopy and ultraviolet visible spectroscopy. Using ion-coupled plasma optical emission spectroscopy, cobalt concentration in the nanocomposites was found to be 80%. In addition, cytotoxicity of graphene/cobalt nanocomposites were evaluated using 3-[4,5-dimethylthiazol-2yl]-2,5-diphenyltetrazolium bromide or MTT assay. MTT viability assay exhibited biocompatibility to L929 mouse fibroblasts cells, under a high dose of 100 μg/mL over 24 h. Hyperthermia results showed the superior conversion of electromagnetic energy into heat at 350 kHz frequency for 0.01 and 0.005 g/L of the nanocomposites solution. The measured heat generation and energy transfer results were anticipated by the finite element analysis, conducted for the 3D structure. Magnetic resonance imaging characteristics also showed that negatively charge graphene/cobalt nanocomposites are suitable for T1-weighted imaging. © 2016 Elsevier B.V.

Related Docs

View other Related Docs

1. Anti-Cancer Activity of New Phosphoramide-Functionalized Graphene Oxides: An Experimental and Theoretical Evaluation, Current Medicinal Chemistry (2023)

2. Recent Advances and Trends in Nanoparticles Based Photothermal and Photodynamic Therapy, Photodiagnosis and Photodynamic Therapy (2022)

3. Hyperthermia of Breast Cancer Tumor Using Graphene Oxide-Cobalt Ferrite Magnetic Nanoparticles in Mice, Journal of Drug Delivery Science and Technology (2021)

Experts (# of related papers)

View all Related Experts

Mehdi Shafee Ardestani (2)

Mohammad Mahdavi (2)

Other Related Docs

4. Dual-Modal Label-Free Genosensor Based on Hemoglobin@Gold Nanocluster Stabilized Graphene Nanosheets for the Electrochemical Detection of Bcr/Abl Fusion Gene, Talanta (2020)

5. Synergistic Effect of Quercetin and Cobalt Ferrite-Graphene Oxide- Based Hyperthermia to Inhibit Expression of Heat Shock Proteins and Induce Apoptosis in Breast Cancer Cells, Pharmaceutical Sciences (2022)

6. Graphene Oxide Negatively Regulates Cell Cycle in Embryonic Fibroblast Cells, International Journal of Nanomedicine (2020)

7. Recent Developments in Graphene and Graphene Oxide: Properties, Synthesis, and Modifications: A Review, ChemistrySelect (2020)

8. Toxicity of Carbon-Based Nanomaterials in the Human Lung: A Comparative In-Vitro Study, Tanaffos (2022)

9. Pegylation of Graphene/Iron Oxide Nanocomposite: Assessment of Release of Doxorubicin, Magnetically Targeted Drug Delivery and Photothermal Therapy, Applied Nanoscience (Switzerland) (2020)

10. Biological Investigation of a Novel Nanocomposite Based on Functionalized Graphene Oxide Nanosheets With Pectin, Silk Fibroin and Zinc Chromite Nanoparticles, Journal of Biotechnology (2022)

11. Bio-Applications of Graphene Composites: From Bench to Clinic, Advanced 2D Materials (2016)

12. Correction To: Pegylation of Graphene/Iron Oxide Nanocomposite: Assessment of Release of Doxorubicin, Magnetically Targeted Drug Delivery and Photothermal Therapy (Applied Nanoscience, (2020), 10, 4, (1205-1217), 10.1007/S13204-020-01255-8), Applied Nanoscience (Switzerland) (2020)

13. Multifunctional Carbon-Based Nanoparticles: Theranostic Applications in Cancer Therapy and Diagnosis, ACS Applied Bio Materials (2023)

14. Decoration of Graphene Oxide Nanosheets With Carboxymethylcellulose Hydrogel, Silk Fibroin and Magnetic Nanoparticles for Biomedical and Hyperthermia Applications, Nanoscale Advances (2022)

15. Theranostic Applications of Graphene-Based Materials in Lung Cancer: A Review, FlatChem (2025)

16. Cancer Therapy and Imaging Through Functionalized Carbon Nanotubes Decorated With Magnetite and Gold Nanoparticles As a Multimodal Tool, Applied Biochemistry and Biotechnology (2020)

17. Synthesis, Characterization and Antifungal Activity of a Novel Formulated Nanocomposite Containing Indolicidin and Graphene Oxide Against Disseminated Candidiasis, Journal de Mycologie Medicale (2018)

18. Enhanced Visible-Light-Driven Photocatalytic Degradation of Emerging Water Contaminants by a Modified Zinc Oxide-Based Photocatalyst; In-Vivo and In-Vitro Toxicity Evaluation of Wastewater and Pco-Treated Water, Separation and Purification Technology (2020)

19. Stable Conductive and Biocompatible Scaffold Development Using Graphene Oxide (Go) Doped Polyaniline (Pani), International Journal of Polymeric Materials and Polymeric Biomaterials (2020)

20. The Theragnostic Potential of Polyaniline-Decorated Magnetic Nanoparticles: A Sorafenib Carrier for Chemo-Photothermal Therapy and Imaging of Hepatocellular Carcinoma, Journal of Drug Delivery Science and Technology (2025)

Style	Citing Format
MLA	Hatamie S, et al.. "Graphene/Cobalt Nanocarrier for Hyperthermia Therapy and Mri Diagnosis." Colloids and Surfaces B: Biointerfaces, vol. 146, no. , 2016, pp. 271-279.
APA	Hatamie S, Ahadian MM, Ghiass MA, Iraji Zad A, Saber R, Parseh B, Oghabian MA, Shanehsazzadeh Zadeh S (2016). Graphene/Cobalt Nanocarrier for Hyperthermia Therapy and Mri Diagnosis. Colloids and Surfaces B: Biointerfaces, 146(), 271-279.
Chicago	Hatamie S, Ahadian MM, Ghiass MA, Iraji Zad A, Saber R, Parseh B, Oghabian MA, Shanehsazzadeh Zadeh S. "Graphene/Cobalt Nanocarrier for Hyperthermia Therapy and Mri Diagnosis." Colloids and Surfaces B: Biointerfaces 146, no. (2016): 271-279.
Harvard	Hatamie S et al. (2016) 'Graphene/Cobalt Nanocarrier for Hyperthermia Therapy and Mri Diagnosis', Colloids and Surfaces B: Biointerfaces, 146(), pp. 271-279.
Vancouver	Hatamie S, Ahadian MM, Ghiass MA, Iraji Zad A, Saber R, Parseh B, et al.. Graphene/Cobalt Nanocarrier for Hyperthermia Therapy and Mri Diagnosis. Colloids and Surfaces B: Biointerfaces. 2016;146():271-279.
BibTex	@article{ author = {Hatamie S and Ahadian MM and Ghiass MA and Iraji Zad A and Saber R and Parseh B and Oghabian MA and Shanehsazzadeh Zadeh S}, title = {Graphene/Cobalt Nanocarrier for Hyperthermia Therapy and Mri Diagnosis}, journal = {Colloids and Surfaces B: Biointerfaces}, volume = {146}, number = {}, pages = {271-279}, year = {2016} }
RIS	TY - JOUR AU - Hatamie S AU - Ahadian MM AU - Ghiass MA AU - Iraji Zad A AU - Saber R AU - Parseh B AU - Oghabian MA AU - Shanehsazzadeh Zadeh S TI - Graphene/Cobalt Nanocarrier for Hyperthermia Therapy and Mri Diagnosis JO - Colloids and Surfaces B: Biointerfaces VL - 146 IS - SP - 271 EP - 279 PY - 2016 ER -

Science Communicator Platform

Authors

Abstract