Expanded Endoscopic Transnasal Approach to the Chordoid Glioma of the Third Ventricle: The First Case Ever Reported Publisher



Zeinalizadeh M^{1, 2} ; Sadrehosseini SM^{1, 3} ; Meybodi KT² ; Sharifabadi AH⁴
Source: Journal of Korean Neurosurgical Society Published:2016

Abstract

Chordoid glioma of the third ventricle is a rare and challenging tumor to surgery because of its unique anatomical location and its close juxtaposition to the neurovascular structures and hypothalamus. The authors report a case of chordoid glioma of the third ventricle in a 43-year-old woman, who presented with headache and somnolence. The tumor was approached by endoscopic transnasal technique with a favorable result. Histopathologic examination disclosed a neoplastic tissue composed of eosinophilic epithelioid cells, mucinous, periodic acid Schiff-diastase positive, extracellular matrix, and scattered lymphoplasmacytic infiltrates. The best treatment option remains controversial. Customarily, the surgical route to remove chordoid glioma is transcranial; however, the undersurface of the optic chiasm and optic nerves preclude an adequate surgical visualization. In contrast, an expanded endoscopic transnasal approach provides a direct midline corridor to this region without any brain retraction. © 2016 The Korean Neurosurgical Society.