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Bioactive Compounds and Biological Activities of Allium Sativum L. Publisher



Abbasi A1 ; Sanej KD1 ; Moradi S1 ; Bazzaz S1 ; Esmaeili A2 ; Ghafourian K3 ; Sabahi S4 ; Lahouty M5 ; Akrami S6 ; Aslani R7 ; Hosseini H1
Authors

Source: Reference Series in Phytochemistry Published:2024


Abstract

The therapeutic properties of the dynamically bioactive components found in garlic (Allium sativum L.), including allicin, alliin, S-allylmercaptocysteine, S-trityl-L-cysteine, ajoene, diallyl sulfide, and S-allyl-cysteine, have attracted a lot of scientific interest from researchers working on related pre-clinical and clinical investigations as well as in the industrial sector. A number of issues about the bioactive chemicals in garlic that are affected by processing, as well as their possible toxicities, pharmacokinetics, and safety profile, need to be investigated in order to confirm garlic’s health benefits for humans. In this chapter, the outcomes of recent experimental and clinical reports are reviewed and the profile of bioactive compounds, metabolism pathway, bioavailability, biological/therapeutic effects, food-related applicability, methods of adulteration detection, potential toxicities, and safety profile of garlic’s derived bio-compounds will be discussed. © Springer Nature Switzerland AG 2024.
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