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Copper Supported Modified Magnetic Carrageenan As a Bio-Based Catalyst for the Synthesis of Novel Scaffolds Bearing the 1,2,3-Triazole Unit Through the Click Reaction Publisher

Summary: Can green catalysts make better drugs? A study shows a copper-based catalyst creates triazole compounds efficiently, advancing eco-friendly drug synthesis. #GreenChemistry #DrugSynthesis

Khaleghi N1 ; Esmkhani M2 ; Noori M2 ; Dastyafteh N2 ; Ghomi MK1 ; Mahdavi M1 ; Sayahi MH3 ; Javanshir S2
Authors

Source: Nanoscale Advances Published:2024


Abstract

The ongoing work delineates the design of a novel library of 1,2,3-triazole-attached phenylacetamides through molecular hybridization of propargyl and phenylacetamide derivatives. Copper-supported modified magnetic carrageenan serves as a green heterogeneous catalyst, ensuring high yield, efficient reaction times, high atom economy, utilization of an environmentally friendly catalyst from a natural source, and a straightforward workup procedure. The successful synthesis of the catalyst is confirmed and evaluated using various analytical techniques, while the synthetic compounds are characterized through 1H NMR and 13C NMR. © 2024 RSC.
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