Mthfr Rs1801133 Polymorphism and Susceptibility to Colorectal Cancer in Iranian Population: Evidence of a Case-Control Study and Meta-Analysis

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Mthfr Rs1801133 Polymorphism and Susceptibility to Colorectal Cancer in Iranian Population: Evidence of a Case-Control Study and Meta-Analysis Publisher

Haerian MS¹ ; Haerian BS² ; Molanaei S³ ; Kosari F⁴ ; Sabeti S⁵ ; Bidarizerehpoosh F⁵ ; Abdolali E⁶ ; Zali MR⁷

Source: Pharmacogenomics Published:2016

Abstract

Several studies have investigated whether MTHFR rs1801133 polymorphism contributes to risk of colorectal cancer (CRC), however the results are inconclusive. Aim: The purpose of this study was to investigate this hypothesis in a case-control study and meta-analysis in Iranian population. Materials & methods: This polymorphism was genotyped in the 2421 subjects (46% CRC patients) from Tehran. Meta-analysis was performed for determining the risk effect size of this polymorphism on CRC. Results: Both case-control study and meta-analysis showed no association between rs1801133 and CRC risk or its features. Conclusion: This study failed to identify an association between the rs1801133 and susceptibility to CRC in Iranian population. © 2016 Future Medicine Ltd.

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Style	Citing Format
MLA	Haerian MS, et al.. "Mthfr Rs1801133 Polymorphism and Susceptibility to Colorectal Cancer in Iranian Population: Evidence of a Case-Control Study and Meta-Analysis." Pharmacogenomics, vol. 17, no. 17, 2016, pp. 1957-1965.
APA	Haerian MS, Haerian BS, Molanaei S, Kosari F, Sabeti S, Bidarizerehpoosh F, Abdolali E, Zali MR (2016). Mthfr Rs1801133 Polymorphism and Susceptibility to Colorectal Cancer in Iranian Population: Evidence of a Case-Control Study and Meta-Analysis. Pharmacogenomics, 17(17), 1957-1965.
Chicago	Haerian MS, Haerian BS, Molanaei S, Kosari F, Sabeti S, Bidarizerehpoosh F, Abdolali E, Zali MR. "Mthfr Rs1801133 Polymorphism and Susceptibility to Colorectal Cancer in Iranian Population: Evidence of a Case-Control Study and Meta-Analysis." Pharmacogenomics 17, no. 17 (2016): 1957-1965.
Harvard	Haerian MS et al. (2016) 'Mthfr Rs1801133 Polymorphism and Susceptibility to Colorectal Cancer in Iranian Population: Evidence of a Case-Control Study and Meta-Analysis', Pharmacogenomics, 17(17), pp. 1957-1965.
Vancouver	Haerian MS, Haerian BS, Molanaei S, Kosari F, Sabeti S, Bidarizerehpoosh F, et al.. Mthfr Rs1801133 Polymorphism and Susceptibility to Colorectal Cancer in Iranian Population: Evidence of a Case-Control Study and Meta-Analysis. Pharmacogenomics. 2016;17(17):1957-1965.
BibTex	@article{ author = {Haerian MS and Haerian BS and Molanaei S and Kosari F and Sabeti S and Bidarizerehpoosh F and Abdolali E and Zali MR}, title = {Mthfr Rs1801133 Polymorphism and Susceptibility to Colorectal Cancer in Iranian Population: Evidence of a Case-Control Study and Meta-Analysis}, journal = {Pharmacogenomics}, volume = {17}, number = {17}, pages = {1957-1965}, year = {2016} }
RIS	TY - JOUR AU - Haerian MS AU - Haerian BS AU - Molanaei S AU - Kosari F AU - Sabeti S AU - Bidarizerehpoosh F AU - Abdolali E AU - Zali MR TI - Mthfr Rs1801133 Polymorphism and Susceptibility to Colorectal Cancer in Iranian Population: Evidence of a Case-Control Study and Meta-Analysis JO - Pharmacogenomics VL - 17 IS - 17 SP - 1957 EP - 1965 PY - 2016 ER -

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