The Critical Role of Faecalibacterium Prausnitzii in Human Health: An Overview Publisher Pubmed



Leylabadlo HE^{1, 2, 3} ; Ghotaslou R^{2, 4} ; Feizabadi MM⁵ ; Farajnia S⁶ ; Moaddab SY⁴ ; Ganbarov K⁷ ; Khodadadi E⁸ ; Tanomand A⁹ ; Sheykhsaran E² ; Yousefi B¹⁰ ; Kafil HS¹
Source: Microbial Pathogenesis Published:2020

Abstract

Faecalibacterium prausnitzii (F. prausnitzii) is one of the most abundant bacterial species in the colon of healthy human adults and representing more than 5% of the total bacterial population. Recently, it has been known as a major actor in human intestinal health and a biosensor. Changes in this species population richness and quantity have been observed in many illnesses and several investigations have reported that abundance of F. prausnitzii is reduced in different intestinal disorders. In the current review, we aim to consider literature from various library databases and electronic searches (Science Direct, PubMed, and Google Scholar) which were randomly collected and serve as an overview of different features of F. prausnitzii including metabolites, anti-inflammatory action, and correlation of dysbiosis of this bacterium with various complications in human. © 2020 Elsevier Ltd