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Renoprotective Efficacy of Montelukast; an Overview on Recent Advancements Publisher



Mojtahedi SY1, 2 ; Ghodsi M3 ; Pourpashang P4
Authors

Source: Journal of Nephropharmacology Published:2025


Abstract

Montelukast holds significant promise as a renoprotective agent, especially in early-stage kidney injuries. Its multifaceted mechanisms—ranging from anti-inflammatory and antioxidant actions to neutrophil inhibition—underscore its potential utility in clinical settings. Montelukast should not be used in patients with a known hypersensitivity to the drug or its components. Caution is advised for individuals with a history of psychiatric disorders or those who have phenylketonuria (PKU), as some formulations contain phenylalanine. © 2025, Society of Diabetic Nephropathy Prevention. All rights reserved.
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