Comparison of Effect of Ventolin and Hypersaline 3% on Recovery Course of Acute Bronchiolitis in Hajar Hospital, Shahrekord in 2013-2014



Zamani MA¹ ; Nourbakhsh MK² ; Rafieian M³ ; Keyvani Hafshejani Z⁴ ; Heidari Soureshjani S⁵
Source: Journal of Zanjan University of Medical Sciences and Health Services Published:2016

Abstract

Background and Objective: Acute bronchiolitis is one of the most common reasons for inflammation, small airways obstruction, and lower respiratory tract infection in infancy. Owing that there has been no study on the efficacy of hypersaline 3% in the treatment of acute bronchiolitis in Iran, the present study was undertaken to deal with this issue. Materials and Methods: This double-blinded clinical trial was carried out in Hajar Hospital of Shahrekord in 2013-2014. 70 patients under 2 years of age with bronchiolitis were assigned to two groups of 35 each. The first group received nebulized Ventolin while the second group was given nebulized hypersaline 3% three times a day. Subsequent to these administrations, recovery duration was compared in both groups. Results: The mean and standard deviation of recovery duration in the Ventolin group was 4.14±0.9 days and in the hypersaline 3% group was 3.06±0.6 days. T-test and mean recovery duration was significantly lower in the hypersaline 3% group (P<0.001). Conclusion: Nebulizer hypersaline 3% had a better therapeutic effect than Ventolin in the treatment of acute bronchiolitis. Therefore, the use of this drug, rather than Ventolin, is recommended for the treatment of acute bronchiolitis in children under two years of age. © 2016, Zanjan University of Medical Sciences and Health Services. All right reserved.