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Engineered Biomimetic Membranes for Organ-On-A-Chip Publisher Pubmed



Rahimnejad M1, 2 ; Rasouli F3 ; Jahangiri S2, 4 ; Ahmadi S5, 6 ; Rabiee N7, 8, 11 ; Ramezani Farani M9 ; Akhavan O7 ; Asadnia M8 ; Fatahi Y10 ; Hong S11 ; Lee J11 ; Lee J11 ; Hahn SK11
Authors

Source: ACS Biomaterials Science and Engineering Published:2022


Abstract

Organ-on-a-chip (OOC) systems are engineered nanobiosystems to mimic the physiochemical environment of a specific organ in the body. Among various components of OOC systems, biomimetic membranes have been regarded as one of the most important key components to develop controllable biomimetic bioanalysis systems. Here, we review the preparation and characterization of biomimetic membranes in comparison with the features of the extracellular matrix. After that, we review and discuss the latest applications of engineered biomimetic membranes to fabricate various organs on a chip, such as liver, kidney, intestine, lung, skin, heart, vasculature and blood vessels, brain, and multiorgans with perspectives for further biomedical applications. © 2022 American Chemical Society. All rights reserved.
1. Liver-On-A-Chip, Principles of Human Organs-on-Chips (2023)
2. Hydrogel Membranes in Organ-On-A-Chip Devices: A Review, Colloids and Surfaces B: Biointerfaces (2025)
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