Studying the Frequency of Helicobacter Pylori Infection Among Women Suffering From Polycystic Ovary Resorting to Hospital Infertility Center Publisher



Darvishi M¹ ; Forootan M³ ; Forootan M³ ; Azmodeh O² ; Matinfar H⁴
Source: Biomedical and Pharmacology Journal Published:2017

Abstract

Polycystic ovary syndrome (PCOS) is in fact a chronic form of anovulation which is usually observed besides a large spectrum of clinical symptoms and signs. Helicobacter pylori is one of the most common infections that afflict humans. Considering the large prevalence of helicobacter pylori, particularly in developing countries, and the possibility of its effect on polycystic ovary syndrome (PCOS), the present research seeks to study the frequency of helicobacter pylori among women suffering from PCOS resorting to the infertility clinic of Mirza Kouchak Khan hospital from 2010 to 2011. A cross-sectional - descriptive research was conducted on 110 patients suffering from PCOS who had resorted to the infertility clinic of Mirza Kouchak Khan hospital from 2010 to 2011. As much as 5 cc blood was taken from the participants and after removing serum, blood samples were stored in a temperature of-20 !. Using ELISA test and in accordance with kit manufacturer's protocol (Trinity Biotech), IgG/IgA antibody titre was measured. The raw data was then analyzed using IBM SPSS Statistics v.15. The average and standard deviation of the age of those suffering from PCOS in this research was 26.55 ± 4.06 years old. The average and standard deviation of patients' BMI in this research was 26.77 ± 4.09. The results of categorizing age group and evaluation of antibody titre (IgA or IgG) showed that people aging 30 to 40 years old exhibited the highest rate in being identified with the positive titre of at least one antibody. The results of assessing IgG and IgA antibody titres by ELISA test showed that those people with a positive IgG titre are much more than those with positive IgA titre. Considering the results of this research and the scientific evidences presented here concerning complications of women's reproduction organs with helicobacter pylori, we may suggest that this bacteria acts as a risk factor in afflicting the patients with PCOS.