Pyostomatitis Vegetans in a Young Woman With Gastrointestinal Symptoms: A Case Report and Review of Literature Publisher



Gholizadeh N¹ ; Aghahosseini F² ; Barati H³ ; Rohani B⁴
Source: Journal of Kerman University of Medical Sciences Published:2021

Abstract

Pyodermatitis-pyostomatitis vegetans (PD-PSV) is an uncommon inflammatory mucocutaneous disease with unknown etiology. It is characterized by pustular and vegetating plaques on the skin and oral mucosa. When the oral mucosa is involved alone, it is called pyostomatitis vegetans. This disease is considered as an oral manifestation of inflammatory bowel diseases. In the present paper, we report a case of pyostomatitis vegetans in a 23-year-old female patient with swelling of the lips and oral lesions. Our patient had simultaneously three important clinical symptoms, including the presence of intra-oral lesions, lip swelling, and gastrointestinal manifestations that may be suggestive of inflammatory bowel disease. Her oral manifestations improved with topical antifungal drug and local and systemic corticosteroids. In addition, the results of our extensive search in reliable scientific databases including Google and PubMed for articles (case reports and literature reviews) containing the keywords: ”pyostomatitis vegetans” and pemphigus vegetans” in recent years are presented. © 2021, Kerman University of Medical Sciences. All rights reserved.