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Prevalence of Human Herpesvirus-8 Among Hiv-Infected Patients, Intravenous Drug Users and the General Population in Iran Publisher Pubmed



Kakavandghalehnoei R1 ; Shoja Z2 ; Najafi A3 ; Mollahoseini MH4 ; Shahmahmoodi S1 ; Marashi SM1 ; Nejati A1 ; Jalilvand S1
Authors

Source: Sexual Health Published:2016


Abstract

Studies looking at the frequency of human herpesvirus-8 (HHV-8) among Iranian blood donors have produced conflicting results. The aim of this study was to investigate the prevalence of HHV-8 DNA by using polymerase chain reaction methods among 168 healthy individuals, 60 intravenous drug users and 100 HIV-infected patients from Iran. The prevalence of HHV-8 was significantly higher among intravenous drug users (13.3%) compared with the general population (3.6%; P≤0.017). The HHV-8 genome was mostly detected among intravenous drug users who displayed high-risk sexual behaviours. Moreover, the HHV-8 genome was also detected in 8% of HIV-infected patients. The present study findings support the likelihood that the transmission of HHV-8 is via a sexual route in the Iranian population. Journal compilation © CSIRO 2016.
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