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The Association Between Healthy Diet Indicator and Phytochemical Index With Prostate Cancer Odds Ratio: A Case-Control Study Publisher Pubmed



Mahmoodi M1, 2 ; Mohammadi F1, 2 ; Rajabzadehdehkordi M1, 3 ; Jalilpiran Y4 ; Makhtoomi M1, 5 ; Nouri M6 ; Faghih S3
Authors

Source: Journal of Health, Population and Nutrition Published:2024


Abstract

Background and objective: Healthy diets and diets rich in phytochemicals can have health-promoting benefits in prostate cancer. Therefore, this study aimed to explore the possible association between Healthy Diet Indicator (HDI) and Phytochemical Index (PI) with prostate cancer odds ratio. Methods: This is a case-control study conducted in Shiraz, Iran, involving 62 newly diagnosed prostate cancer cases and 63 hospital-based controls. The study collected demographic and anthropometric data, as well as dietary intake information via a semi-quantitative food frequency questionnaire. Logistic regression models were employed to evaluate the association between HDI and PI with prostate cancer. Results: The study included 120 participants and found that individuals with higher HDI and PI scores had a lower odds ratio of prostate cancer (HDI: odds ratio (OR): 0.322 – confidence interval (CI) 95%: 0.14–0.700 - PI: OR: 0.426 - CI 95%: 0.204–0.888). After adjusting for potential confounders, a lower odds ratio of prostate cancer was observed specifically among those with higher HDI scores (OR: 0.376 - CI 95%: 0.163–0.868). Conclusion: The findings of the present study suggest that adopting healthier dietary habits rich in dietary phytochemicals could be effective in preventing and halting the progression of prostate cancer. © The Author(s) 2024.
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