Iranian Deep Brain Stimulation Registry for Parkinson’S Disease (Idbsr-Pd): Establishment and Feasibility Study Publisher



Abdollahifard S ; Maghsoodzadeh S ; Rezaei R ; Najibi A ; Heidarian A ; Haghighi M M ; Khademi F ; Sabet S ; Torabzade Tari S ; Karimi A ; Razmkon A ; Jaafari N
Source: Acta Neurologica Belgica Published:2026

Abstract

Background: Deep Brain Stimulation (DBS) is an established treatment for advanced Parkinson’s disease (PD), yet registry-based data from developing countries remain limited. This study reports the establishment and feasibility of the Iranian Deep Brain Stimulation Registry for Parkinson’s Disease (IDBSR-PD). Methods: We conducted a single-center feasibility study at the Research Center for Neuromodulation and Pain, including all PD patients undergoing DBS implantation since 2014. Primary feasibility outcomes included patient enrollment coverage, follow-up adherence, data completeness, multidisciplinary implementation, and the sustainability of technical infrastructure. Secondary outcomes included descriptive patient characteristics. Only descriptive statistics were performed; no hypothesis testing or longitudinal outcome analyses were conducted. Results: A total of 208 patients were enrolled (65.4% male; mean age 58.4 ± 10.2 years). Enrollment increased progressively over time, peaking in 2024 (n = 41). Patients were referred from multiple provinces across Iran. Data validation mechanisms and regular surveillance ensured acceptable data completeness. Conclusions: The IDBSR-PD demonstrates the feasibility and sustainability of a web-based DBS registry in a developing country. These findings confirm the viability of structured data collection and provide a foundation for future multicenter and longitudinal outcome research. © The Author(s) under exclusive licence to Belgian Neurological Society 2026.