An Enhanced Electrochemiluminescence Sensor Modified With a Ru(Bpy)3 2 +/Yb2o3 Nanoparticle/Nafion Composite for the Analysis of Methadone Samples Publisher Pubmed



Hosseini M^{1, 2} ; Pur MRK³ ; Norouzi P^{3, 4} ; Moghaddam MR³ ; Ganjali MR^{3, 4}
Source: Materials Science and Engineering C Published:2017

Abstract

The sensitive interaction between Ru(bpy)3 2 + and methadone was used for the modification of a solid-state electrochemiluminescence electrode, and it was also successfully applied to determine methadone in the samples. The working electrode was made of a Yb2O3 − containing modified carbon paste electrode. The presence of Yb2O3 nanoparticles in the structure of the electrode, was found to enhance its sensitizing effect towards the Ru(bpy)3 2 +-methadone electrochemiluminescence system. The electrodes with the optimal make-up revealed a linear ECL-concentration behavior from 5 × 10− 9–3 × 10− 7 M and reached method detection limit as low as 2.1 × 10− 10 M with a relative standard deviation of 4.4% (S/N = 3). This modified ECL could present a simple yet sensitive and selective route for the determination of methadone in different samples. © 2017 Elsevier B.V.