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An Update on the Anti-Diabetic Functions of Genistein: A Soybean (Glycine Max (L.) Merr.) Isoflavone Publisher



Sharifinejad N1, 9 ; Hooshyar M2 ; Ramezankhah M3 ; Shamsehkohan A4 ; Saie R5 ; Sahebjam M4 ; Aleebrahimdehkordi E6 ; Orandi S7 ; Faraji A8 ; Deravi N2
Authors

Source: Current Traditional Medicine Published:2024


Abstract

Type 2 diabetes mellitus (T2DM) is a developing worldwide issue. Traditionally, different plants have been used throughout history to lower blood glucose and improve the impact of diabetes. Also, today, many natural products have been introduced to lower blood glucose in T2DM patients. The beneficial effects of genistein, the most essential and abundant isoflavone of soybean (Glycine max (L.) Merr.), on blood glucose and other metabolic indicators, as well as diabetesrelated complications, have been widely investigated. In the current narrative review, through a thorough search from 2013-2020” in “PubMed, Scopus, “ResearchGate”, “Google Scholar”, and Web of Science databases, we have retrieved, reviewed, and summarized all clinical trials, as well as in vitro and in vivo studies on the anti-diabetic potential of genistein. © 2024 Bentham Science Publishers.
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