Tio2-Based Nanocomposites for Cancer Diagnosis and Therapy: A Comprehensive Review Publisher



Pourmadadi M¹ ; Rajabzadehkhosroshahi M¹ ; Eshaghi MM¹ ; Rahmani E^{1, 2} ; Motasadizadeh H^{3, 4} ; Arshad R⁵ ; Rahdar A⁶ ; Pandey S⁷
Source: Journal of Drug Delivery Science and Technology Published:2023

Abstract

In biomedical engineering, researchers have begun to focus on improving the physiochemical properties of TiO2 (titania) through modification. The purpose of this paper is to present a comprehensive review of the potential applications of nanoscale TiO2 and its nanocomposites in the biomedical field, specifically in cancer therapeutics. Titania-based nanomaterials’ usage in biosensors have been widely explored by researchers, especially in the electrochemical class. A range of bioimaging approaches, including FL, PA, CT, PET, MR, and multi-mode imaging, have been evaluated to assess their applicability. Moreover, nanoscale titania has been identified as a popular candidate for different methods of cancer treatment including phototherapy, chemotherapy, and microwave hyperthermia. As a final point, a multifunctional nanoplatform to treat cancer has been developed through a combination of multiple treatment methods. © 2023 Elsevier B.V.