Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
Covid-19 in Transplant Recipient Children: An Iranian Referral Hospital-Based Study Publisher Pubmed



Esslami GG1, 2 ; Mahmoudi S3 ; Navaeian A4 ; Behfar M5 ; Hamidieh AA5 ; Alimadadi H6 ; Mahmoudieh Y7 ; Mamishi S3, 4
Authors

Source: Acta Biomedica Published:2021


Abstract

To our knowledge, there is still very limited information on the severity, mortality, laboratory, and radiologic findings of COVID-19 infection in transplant patients, particularly children. In this study, we reported 7 transplant recipients with laboratory-confirmed COVID-19 infection. The median age was 7.5 years (IQR: 31month-10 years), and 71% of the patients were male. All cases presented with a fever. The median duration of fever before admission was 2 days (IQR:1-8 days). Five patients (71%) experienced cough and dyspnea. Lymphocytopenia (Median of 0.6 (IQR: 0.14-2.0× 109 cells per L) and thrombocytopenia (Median of 65 (IQR: 49-201× 109 cells per L) were the most common CBC findings (both seen in 5 out of the 7 patients. Among 4 of the patients who underwent CT scans, 2 had ground glass opacity and consolidations. The mean number of lobe involvement in our patients was 3 (0-5), and 75% of the cases showed bilateral lung involvement in the imaging. In 4 patients (51%) the disease course manifested severely, and 2 patients are now deceased (28.6%). In conclusion, immunocompromised pediatric subgroups may experience higher rates of disease severity and mortality in comparison with the immunocompetent pediatric population. (www. actabiomedica.it). © Mattioli 1885.
Other Related Docs
4. Dynamic Changes of Lymphocyte Subsets in the Course of Covid-19, International Archives of Allergy and Immunology (2021)
19. Computed Tomography Findings in 3,557 Covid-19 Infected Children: A Systematic Review, Quantitative Imaging in Medicine and Surgery (2021)