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A Transition-Metal-Free Fast Track to Flavones and 3-Arylcoumarins Publisher Pubmed



Golshani M1, 2 ; Khoobi M1, 3 ; Jalalimanesh N2 ; Jafarpour F2 ; Ariafard A4, 5
Authors

Source: Chemical Communications Published:2017


Abstract

A highly regioselective and transition-metal free one-pot arylation of chromenones with arylboronic acids has been achieved employing K2S2O8. The procedure consists of a sequence of some reactions including an arylation/decarboxylation cascade and proceeds well in aqueous media to afford biologically interesting flavones and 3-arylcoumarins. This method exhibited excellent selectivity and functional group tolerance under mild conditions. The reaction also showed perfect efficacy for the preparation of styryl coumarins. This journal is © 2017 The Royal Society of Chemistry.