Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
Bacterial Biofilm in Colorectal Cancer: What Is the Real Mechanism of Action? Publisher Pubmed



Mirzaei R1 ; Mirzaei H2 ; Alikhani MY1 ; Sholeh M3 ; Arabestani MR1 ; Saidijam M4, 5, 6 ; Karampoor S7 ; Ahmadyousefi Y5, 6 ; Moghadam MS8 ; Irajian GR3 ; Hasanvand H9 ; Yousefimashouf R1
Authors

Source: Microbial Pathogenesis Published:2020


Abstract

Human colorectal cancer is the third most common cancer around the world. Colorectal cancer has various risk factors, but current works have bolded a significant activity for the microbiota of the human colon in the development of this disease. Bacterial biofilm has been mediated to non-malignant pathologies like inflammatory bowel disease but has not been fully documented in the setting of colorectal cancer. The investigation has currently found that bacterial biofilm is mediated to colon cancer in the human and linked to the location of human cancer, with almost all right-sided adenomas of colon cancers possessing bacterial biofilm, whilst left-sided cancer is rarely biofilm positive. The profound comprehension of the changes in colorectal cancer can provide interesting novel concepts for anticancer treatments. In this review, we will summarize and examine the new knowledge about the links between colorectal cancer and bacterial biofilm. © 2020
2. Intestinal Microbiota: Novel Personalized Cancer Immunotherapy in Colorectal Cancer, International Archives of Allergy and Immunology (2022)
3. Role of Gut Microbiota in the Pathogenesis of Colorectal Cancer; a Review Article, Gastroenterology and Hepatology from Bed to Bench (2018)
Experts (# of related papers)
Other Related Docs
9. Gut Microbiota, Epigenetic Modification and Colorectal Cancer, Iranian Journal of Microbiology (2017)
11. Tumor Immunology, Clinical Immunology (2022)
18. The Microbiome in Precision Medicine: A New Approach to Cancer Treatment, Journal of Mazandaran University of Medical Sciences (2021)