Degradation and Biodegradability Enhancement of Chloramphenicol and Azithromycin in Aqueous Solution Using Heterogeneous Catalytic Ozonation in the Presence of Mgo Nanocrystalin Comparison With Single Ozonation



Arfaeinia H¹ ; Sharafi K^{2, 3} ; Banafshehafshan S¹ ; Hashemi SE³
Source: International Journal of Pharmacy and Technology Published:2016

Abstract

The catalytized ozonation of antibiotic solution in the presence of Mg Onanocrystal as a catalyst was studied in a pilot scale batch reactor. The effects of various variables such as pH (3–13), reaction time, MgO dosage (0–10 g/L), and initial antibiotic concentration (0–50 mg/L) on CAP and AZM removal were investigated, and the results were compared to non-catalyzed ozonation. The optimized pH and catalyst dosage were found to be 8.5 and 6 g/L, respectively. The complete removal of CAP was found in COP at this optimum condition for an antibiotic concentration of 50 mg/L at a reaction time as little as 6 min, while the time needed to achieve the similar removal at conventional ozonation was 30 min. Moreover, the catalytized ozonation can significantly enhance the BOD5 /COD ratio from below 0.1 in untreated solution to 0.41 to 0.68 for treated solutions; therefore, antibiotic was transformed to biodegradable substances. Thus, the COP with MgOnanocrystalscanbe taken into account as an feasible and effective technique for pre-treating the antibiotic-laden solutions, allowing the final-purified of the effluent in a biological treatment plant. © 2016, International Journal of Pharmacy and Technology. All rights reserved.