Bacterial Community of Chronic Rhinosinusitis Patients and Therapeutic Ultrasound Efficacy: Clinical Trial Study Publisher



Feizabadi N¹ ; Sarrafzadeh J¹ ; Fathali M² ; Vasaghigharamaleki B³ ; Dadgoo M¹ ; Kardanyamchi J⁴ ; Kazemian H⁵ ; Hesamshariati S⁶ ; Feizabadi MM⁴
Source: Iranian Journal of Microbiology Published:2022

Abstract

Background and Objectives: Bacterial involvement in chronic rhinosinusitis (CRS) condition made it difficult to treat using available antibiotic therapy. Therapeutic ultrasound was investigated here to evaluate bacterial diversity and quantity before and after continuous/pulsed ultrasound strategy compared to control patients. Materials and Methods: Totally, 34 CRS patients were studied in three groups, including continuous ultrasound, pulsed ultrasound and control. Bacterial culture and identification were done before and after treatment. Computed tomography scan (CT scan) and questionnaire scores were recorded two times before and after intervention. Results: The most prevalent bacterial isolates were non-hemolytic Streptococci (34 patients), coagulase-negative Staphylococcus (33 patients), Gram-negative cocci (26 patients), Staphylococcus aureus (19 patients), Streptococcus pneumoniae (five patients) and Streptococcus pyogenes (five patients). Both continuous and pulsed ultrasound could significantly reduce the quantity of bacterial isolates after treatment. CT scan and questionnaire results support the effectiveness of therapeutic ultrasound. Conclusion: The quantity of clinically important bacteria was significantly reduced using ultrasound treatment and recovery of patients was supported by CT scan and questionnaire scores. Alternative therapeutic ultrasound could be an effective procedure in CRS patients. © 2022 The Authors. Published by Tehran University of Medical Sciences.