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Prevalence and Phylogenic Study of Human T-Lymphotropic Virus 1 in Patients With Thalassemia in the Northeast of Iran Publisher



Abedi F1, 2 ; Mozhgani SH3 ; Rahimzadegan M2 ; Gudarzi H3 ; Valizadeh N4 ; Rezaee SA4
Authors

Source: Future Virology Published:2017


Abstract

Aim: This study aimed to investigate the frequency and phylogenetic distribution of human T-lymphotropic virus type 1 (HTLV-1) in thalassemia cases. Methods: Between 2006 and 2013, a total of 100 thalassemic individuals were investigated for HTLV-1 infections. Results: Four people (4%) were reactive for HTLV antibodies. No considerable correlation was seen between factors such as age, blood transfusion history, surgery, marital status, gender and blood types. All HTLV-1 sequences belonged to the transcontinental (A) subgroup in the cosmopolitan (a) subtype. Conclusion: In addition to phylogenetic distribution, our results demonstrate that the prevalence of HTLV-1 infection among thalassemia patients in Mashhad is higher than that of previous studies. © 2017 Future Medicine Ltd.
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