Epigenetic Modifications in Gastric Cancer: Focus on Dna Methylation

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Epigenetic Modifications in Gastric Cancer: Focus on Dna Methylation Publisher Pubmed

Ebrahimi V^{1, 2} ; Soleimanian A^{1, 3} ; Ebrahimi T⁴ ; Azargun R⁵ ; Yazdani P¹ ; Eyvazi S⁶ ; Tarhriz V¹

Source: Gene Published:2020

Abstract

Gastric cancer is a complex heterogeneous disease which is the fourth prevalent malignancy worldwide. Although, several diagnosis and treatment are available for the gastric cancer patients, however the malignancy is still the third leading cause of cancer-related death in the world. Beside the genetic and environmental factors, epigenetic alterations are also involved in the emergence of gastric cancer. Epigenetics alterations are heritable changes which regulate gene expression without occurring changes in DNA sequence. Epigenetic changes mostly include DNA methylation, histon post-translational modifications, chromatin remodeling and non-coding RNAs. Among the mentioned epigenetic modifications, DNA methylation is a major epigenetic process that plays a key role in different stages of evolution and cancer development. In this review, we address all types of related epigenetic modifications in gastric cancer by focus on DNA methylation by reviewing the recent literatures. Understanding of molecular mechanisms of epigenetics alterations in gastric cancer development helps researchers to identify new epigenetic drugs against the malignancy. © 2020

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Style	Citing Format
MLA	Ebrahimi V, et al.. "Epigenetic Modifications in Gastric Cancer: Focus on Dna Methylation." Gene, vol. 742, no. , 2020, pp. -.
APA	Ebrahimi V, Soleimanian A, Ebrahimi T, Azargun R, Yazdani P, Eyvazi S, Tarhriz V (2020). Epigenetic Modifications in Gastric Cancer: Focus on Dna Methylation. Gene, 742(), -.
Chicago	Ebrahimi V, Soleimanian A, Ebrahimi T, Azargun R, Yazdani P, Eyvazi S, Tarhriz V. "Epigenetic Modifications in Gastric Cancer: Focus on Dna Methylation." Gene 742, no. (2020): -.
Harvard	Ebrahimi V et al. (2020) 'Epigenetic Modifications in Gastric Cancer: Focus on Dna Methylation', Gene, 742(), pp. -.
Vancouver	Ebrahimi V, Soleimanian A, Ebrahimi T, Azargun R, Yazdani P, Eyvazi S, et al.. Epigenetic Modifications in Gastric Cancer: Focus on Dna Methylation. Gene. 2020;742():-.
BibTex	@article{ author = {Ebrahimi V and Soleimanian A and Ebrahimi T and Azargun R and Yazdani P and Eyvazi S and Tarhriz V}, title = {Epigenetic Modifications in Gastric Cancer: Focus on Dna Methylation}, journal = {Gene}, volume = {742}, number = {}, pages = {-}, year = {2020} }
RIS	TY - JOUR AU - Ebrahimi V AU - Soleimanian A AU - Ebrahimi T AU - Azargun R AU - Yazdani P AU - Eyvazi S AU - Tarhriz V TI - Epigenetic Modifications in Gastric Cancer: Focus on Dna Methylation JO - Gene VL - 742 IS - SP - EP - PY - 2020 ER -

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