Successful Treatment of Multiorgan Toxicity Induced by Explosive Agent With Repeated Hemodialysis: A Case Report Publisher



Arefi M¹ ; Mohammadi H^{1, 2, 3}
Source: Jundishapur Journal of Natural Pharmaceutical Products Published:2016

Abstract

Introduction: Acute poisoning by oral ingestion of mixed hazardous materials can lead to multiorgan toxicity and may representa special challenge in clinical management, in particular if little is known about the effects of the involved agents. This is especiallytrue when industrial chemical substances have been swallowed, as a huge variety of toxic substances must be taken into account.Case Presentation: This case report describes the management of this potentially life-threatening situation in a 21-year-old manwith multiorgan system failure, who developed gastrointestinal bleeding, anemia, renal dysfunction, altered visual acuity, seizure,jaundice, and ascites due to multiorgan toxicity. This patient was successfully treated with repeated hemodialysis, and survived. Hewas discharged from the hospital with an acceptable level of morbidity.Conclusions: In cases of oral-based multiple hazardous substance toxicity without a specific antidote, hemodialysis seems to be thebest treatment. The problems created by multiorgan toxicity and the issues involved in the decision-making process are discussedin the management of this extraordinarily overwhelming complication. © 2016, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences.