The Prevalence of Inflammatory Bowel Disease (Ibd) in Patients With Multiple Sclerosis (Ms): A Systematic Review and Meta-Analysis Publisher



Nasirzadeh A¹ ; Jahanshahi R² ; Ghajarzadeh M³ ; Mohammadi A⁴ ; Moghadasi AN¹
Source: International Journal of Preventive Medicine Published:2023

Abstract

Background: This systematic review and meta-analysis aim to update the pooled prevalence of Inflammatory bowel disease (IBD) in patients with multiple sclerosis (MS). Methods: Two researchers independently and systematically searched PubMed, Scopus, EMBASE, Web of Science, and google scholar. They also searched for references of the included studies, and conference abstracts that were published up to September 2021. Results: The literature search revealed 5719 articles, after deleting duplicates 3616 remained. Finally, 17 studies were included. The pooled prevalence of IBD in MS was 1% (I 2 = 96.3%, P < 0.001). The pooled odds ratio of developing IBD in MS cases was 1.36 (95% CI: 1.1-1.6) (I 2 = 58.3, P = 0.01). Conclusions: The results of this systematic review and meta-analysis show that the pooled prevalence of IBD in MS patients was 1% and the pooled odds ratio of developing IBD in MS cases was 1.36. © 2023 International Journal of Preventive Medicine | Published by Wolters Kluwer - Medknow.