Stem Cell Transplantation for Diamond–Blackfan Anemia. a Retrospective Study on Behalf of the Severe Aplastic Anemia Working Party of the European Blood and Marrow Transplantation Group (Ebmt)

Stem Cell Transplantation for Diamond–Blackfan Anemia. a Retrospective Study on Behalf of the Severe Aplastic Anemia Working Party of the European Blood and Marrow Transplantation Group (Ebmt) Publisher Pubmed

Miano M¹ ; Eikema DJ² ; De La Fuente J³ ; Bosman P² ; Ghavamzadeh A⁴ ; Smiers F⁵ ; Sengelov H⁶ ; Yesilipek A⁷ ; Formankova R⁸ ; Bader P⁹ ; Diaz Perez MA¹⁰ ; Bertrand Y¹¹ ; Niemeyer C¹² ; Diallo S¹³ Show All Authors

Miano M¹
Eikema DJ²
De La Fuente J³
Bosman P²
Ghavamzadeh A⁴
Smiers F⁵
Sengelov H⁶
Yesilipek A⁷
Formankova R⁸
Bader P⁹
Diaz Perez MA¹⁰
Bertrand Y¹¹
Niemeyer C¹²
Diallo S¹³
Ansari M¹⁴
Bykova TA¹⁵
Faraci M¹⁶
Bonanomi S¹⁷
Gozdzik J¹⁸
Satti TM¹⁹
Bodova I²⁰
Wolfl M²¹
Rocha VG²²
Mellgren K²³
Rascon J²⁴
Holter W²⁵
Lange A²⁶
Meisel R²⁷
Beguin Y²⁸
Mozo Y²⁹
Krivan G³⁰
Sirvent A³¹
Bruno B³²
Dalle JH³³
Onofrillo D³⁴
Giardino S¹⁶
Risitano AM³⁵
De Latour RP³⁶
Dufour C¹

Source: Transplantation and Cellular Therapy Published:2021

Abstract

Data on stem cell transplantation (SCT) for Diamond–Blackfan Anemia (DBA) is limited. We studied patients transplanted for DBA and registered in the EBMT database. Between 1985 and 2016, 106 DBA patients (median age, 6.8 years) underwent hematopoietic stem cell transplantation from matched-sibling donors (57%), unrelated donors (36%), or other related donors (7%), using marrow (68%), peripheral blood stem cells (20%), both marrow and peripheral blood stem cells (1%), or cord blood (11%). The cumulative incidence of engraftment was 86% (80% to 93%), and neutrophil recovery and platelet recovery were achieved on day +18 (range, 16 to 20) and +36 (range, 32 to 43), respectively. Three-year overall survival and event-free survival were 84% (77% to 91%) and 81% (74% to 89%), respectively. Older patients were significantly more likely to die (hazard ratio, 1.4; 95% confidence interval, 1.06 to 1.23; P <.001). Outcomes were similar between sibling compared to unrelated-donor transplants. The incidence of acute grades II to IV of graft-versus-host disease (GVHD) was 30% (21% to 39%), and the incidence of extensive chronic GVHD was 15% (7% to 22%). This study shows that SCT may represent an alternative therapeutic option for transfusion-dependent younger patients. © 2021

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Amir Ali Hamidieh (5)

Amir Kasaeian (4)

Style	Citing Format
MLA	Miano M, et al.. "Stem Cell Transplantation for Diamond–Blackfan Anemia. a Retrospective Study on Behalf of the Severe Aplastic Anemia Working Party of the European Blood and Marrow Transplantation Group (Ebmt)." Transplantation and Cellular Therapy, vol. 27, no. 3, 2021, pp. 274.e1-274.e5.
APA	Miano M, Eikema DJ, De La Fuente J, Bosman P, Ghavamzadeh A, Smiers F, Sengelov H, Yesilipek A, Formankova R, Bader P, Diaz Perez MA, Bertrand Y, Niemeyer C, Diallo S, Ansari M, Bykova TA, Faraci M, Bonanomi S, Gozdzik J, ... Dufour C (2021). Stem Cell Transplantation for Diamond–Blackfan Anemia. a Retrospective Study on Behalf of the Severe Aplastic Anemia Working Party of the European Blood and Marrow Transplantation Group (Ebmt). Transplantation and Cellular Therapy, 27(3), 274.e1-274.e5.
Chicago	Miano M, Eikema DJ, De La Fuente J, Bosman P, Ghavamzadeh A, Smiers F, Sengelov H, et al.. "Stem Cell Transplantation for Diamond–Blackfan Anemia. a Retrospective Study on Behalf of the Severe Aplastic Anemia Working Party of the European Blood and Marrow Transplantation Group (Ebmt)." Transplantation and Cellular Therapy 27, no. 3 (2021): 274.e1-274.e5.
Harvard	Miano M et al. (2021) 'Stem Cell Transplantation for Diamond–Blackfan Anemia. a Retrospective Study on Behalf of the Severe Aplastic Anemia Working Party of the European Blood and Marrow Transplantation Group (Ebmt)', Transplantation and Cellular Therapy, 27(3), pp. 274.e1-274.e5.
Vancouver	Miano M, Eikema DJ, De La Fuente J, Bosman P, Ghavamzadeh A, Smiers F, et al.. Stem Cell Transplantation for Diamond–Blackfan Anemia. a Retrospective Study on Behalf of the Severe Aplastic Anemia Working Party of the European Blood and Marrow Transplantation Group (Ebmt). Transplantation and Cellular Therapy. 2021;27(3):274.e1-274.e5.
BibTex	@article{ author = {Miano M and Eikema DJ and De La Fuente J and Bosman P and Ghavamzadeh A and Smiers F and Sengelov H and Yesilipek A and Formankova R and Bader P and Diaz Perez MA and Bertrand Y and Niemeyer C and Diallo S and Ansari M and Bykova TA and Faraci M and Bonanomi S and Gozdzik J and Satti TM and Bodova I and Wolfl M and Rocha VG and Mellgren K and Rascon J and Holter W and Lange A and Meisel R and Beguin Y and Mozo Y and Krivan G and Sirvent A and Bruno B and Dalle JH and Onofrillo D and Giardino S and Risitano AM and De Latour RP and Dufour C}, title = {Stem Cell Transplantation for Diamond–Blackfan Anemia. a Retrospective Study on Behalf of the Severe Aplastic Anemia Working Party of the European Blood and Marrow Transplantation Group (Ebmt)}, journal = {Transplantation and Cellular Therapy}, volume = {27}, number = {3}, pages = {274.e1-274.e5}, year = {2021} }
RIS	TY - JOUR AU - Miano M AU - Eikema DJ AU - De La Fuente J AU - Bosman P AU - Ghavamzadeh A AU - Smiers F AU - Sengelov H AU - Yesilipek A AU - Formankova R AU - Bader P AU - Diaz Perez MA AU - Bertrand Y AU - Niemeyer C AU - Diallo S AU - Ansari M AU - Bykova TA AU - Faraci M AU - Bonanomi S AU - Gozdzik J AU - Satti TM AU - Bodova I AU - Wolfl M AU - Rocha VG AU - Mellgren K AU - Rascon J AU - Holter W AU - Lange A AU - Meisel R AU - Beguin Y AU - Mozo Y AU - Krivan G AU - Sirvent A AU - Bruno B AU - Dalle JH AU - Onofrillo D AU - Giardino S AU - Risitano AM AU - De Latour RP AU - Dufour C TI - Stem Cell Transplantation for Diamond–Blackfan Anemia. a Retrospective Study on Behalf of the Severe Aplastic Anemia Working Party of the European Blood and Marrow Transplantation Group (Ebmt) JO - Transplantation and Cellular Therapy VL - 27 IS - 3 SP - 274.e1 EP - 274.e5 PY - 2021 ER -

Style

Citing Format

MLA

Miano M, et al.. "Stem Cell Transplantation for Diamond–Blackfan Anemia. a Retrospective Study on Behalf of the Severe Aplastic Anemia Working Party of the European Blood and Marrow Transplantation Group (Ebmt)." Transplantation and Cellular Therapy, vol. 27, no. 3, 2021, pp. 274.e1-274.e5.

APA

Miano M, Eikema DJ, De La Fuente J, Bosman P, Ghavamzadeh A, Smiers F, Sengelov H, Yesilipek A, Formankova R, Bader P, Diaz Perez MA, Bertrand Y, Niemeyer C, Diallo S, Ansari M, Bykova TA, Faraci M, Bonanomi S, Gozdzik J, ... Dufour C (2021). Stem Cell Transplantation for Diamond–Blackfan Anemia. a Retrospective Study on Behalf of the Severe Aplastic Anemia Working Party of the European Blood and Marrow Transplantation Group (Ebmt). Transplantation and Cellular Therapy, 27(3), 274.e1-274.e5.

Chicago

Miano M, Eikema DJ, De La Fuente J, Bosman P, Ghavamzadeh A, Smiers F, Sengelov H, et al.. "Stem Cell Transplantation for Diamond–Blackfan Anemia. a Retrospective Study on Behalf of the Severe Aplastic Anemia Working Party of the European Blood and Marrow Transplantation Group (Ebmt)." Transplantation and Cellular Therapy 27, no. 3 (2021): 274.e1-274.e5.

Harvard

Miano M et al. (2021) 'Stem Cell Transplantation for Diamond–Blackfan Anemia. a Retrospective Study on Behalf of the Severe Aplastic Anemia Working Party of the European Blood and Marrow Transplantation Group (Ebmt)', Transplantation and Cellular Therapy, 27(3), pp. 274.e1-274.e5.

Vancouver

Miano M, Eikema DJ, De La Fuente J, Bosman P, Ghavamzadeh A, Smiers F, et al.. Stem Cell Transplantation for Diamond–Blackfan Anemia. a Retrospective Study on Behalf of the Severe Aplastic Anemia Working Party of the European Blood and Marrow Transplantation Group (Ebmt). Transplantation and Cellular Therapy. 2021;27(3):274.e1-274.e5.

BibTex

@article{ author = {Miano M and Eikema DJ and De La Fuente J and Bosman P and Ghavamzadeh A and Smiers F and Sengelov H and Yesilipek A and Formankova R and Bader P and Diaz Perez MA and Bertrand Y and Niemeyer C and Diallo S and Ansari M and Bykova TA and Faraci M and Bonanomi S and Gozdzik J and Satti TM and Bodova I and Wolfl M and Rocha VG and Mellgren K and Rascon J and Holter W and Lange A and Meisel R and Beguin Y and Mozo Y and Krivan G and Sirvent A and Bruno B and Dalle JH and Onofrillo D and Giardino S and Risitano AM and De Latour RP and Dufour C}, title = {Stem Cell Transplantation for Diamond–Blackfan Anemia. a Retrospective Study on Behalf of the Severe Aplastic Anemia Working Party of the European Blood and Marrow Transplantation Group (Ebmt)}, journal = {Transplantation and Cellular Therapy}, volume = {27}, number = {3}, pages = {274.e1-274.e5}, year = {2021} }

RIS

TY - JOUR
AU - Miano M
AU - Eikema DJ
AU - De La Fuente J
AU - Bosman P
AU - Ghavamzadeh A
AU - Smiers F
AU - Sengelov H
AU - Yesilipek A
AU - Formankova R
AU - Bader P
AU - Diaz Perez MA
AU - Bertrand Y
AU - Niemeyer C
AU - Diallo S
AU - Ansari M
AU - Bykova TA
AU - Faraci M
AU - Bonanomi S
AU - Gozdzik J
AU - Satti TM
AU - Bodova I
AU - Wolfl M
AU - Rocha VG
AU - Mellgren K
AU - Rascon J
AU - Holter W
AU - Lange A
AU - Meisel R
AU - Beguin Y
AU - Mozo Y
AU - Krivan G
AU - Sirvent A
AU - Bruno B
AU - Dalle JH
AU - Onofrillo D
AU - Giardino S
AU - Risitano AM
AU - De Latour RP
AU - Dufour C
TI - Stem Cell Transplantation for Diamond–Blackfan Anemia. a Retrospective Study on Behalf of the Severe Aplastic Anemia Working Party of the European Blood and Marrow Transplantation Group (Ebmt)
JO - Transplantation and Cellular Therapy
VL - 27
IS - 3
SP - 274.e1
EP - 274.e5
PY - 2021
ER -

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Abstract