Current Evidence Regarding Alternative Techniques for Enterocystoplasty Using Regenerative Medicine Methods: A Systematic Review Publisher Pubmed



Arabzadeh Bahri R^{1, 2} ; Peisepar M^{2, 3} ; Maleki S⁴ ; Esmaeilpur Abianeh F^{2, 3} ; A Basti F⁵ ; Kolahdooz A⁶
Source: European Journal of Medical Research Published:2024

Abstract

Enterocystoplasty is the most commonly used treatment for bladder reconstruction. However, it has some major complications. In this study, we systematically reviewed the alternative techniques for enterocystoplasty using different scaffolds. A comprehensive search was conducted in PubMed, Embase, and Cochrane Library, and a total of 10 studies were included in this study. Five different scaffolds were evaluated, including small intestinal submucosa (SIS), biodegradable scaffolds seeded with autologous bladder muscle and urothelial cells, dura mater, human cadaveric bladder acellular matrix graft, and bovine pericardium. The overall results revealed that bladder reconstruction using regenerative medicine is an excellent alternative method to enterocystoplasty regarding the improvement of bladder capacity, bladder compliance, and maximum detrusor pressure; however, more large-scale studies are required. © The Author(s) 2024.