Facile Access to New Pyrido[2,3-D]Pyrimidine Derivatives

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):

Share By

Facile Access to New Pyrido[2,3-D]Pyrimidine Derivatives Publisher Pubmed

Ghaedi A¹ ; Bardajee GR¹ ; Mirshokrayi A¹ ; Mahdavi M² ; Akbarzadeh T^{3, 4}

Source: Molecular Diversity Published:2019

Abstract

Abstract: In this report, a facile, operationally, simple and highly efficient one-pot coupling of 2,6-diaminopyrimidin-4(3H)-one and ethyl-2,4-dioxo-4-phenylbutanoate derivatives is reported. This method afforded a novel series of ethyl-2-amino-3,4-dihydro-4-oxo-5-phenyl pyrido[2,3-d] pyrimidine-7-carboxylate heterocycle derivatives in high yields under refluxing AcOH. Graphical abstract: [Figure not available: see fulltext.]. © 2018, Springer International Publishing AG, part of Springer Nature.

Related Docs

View other Related Docs

1. Furo, Pyrano, and Pyrido[2,3-D]Pyrimidines: A Comprehensive Review of Synthesis and Medicinal Applications, ChemistrySelect (2024)

2. Facile, Novel and Efficient Synthesis of New Pyrazolo[3,4-B]Pyridine Products From Condensation of Pyrazole-5-Amine Derivatives and Activated Carbonyl Groups, RSC Advances (2015)

3. Facile One-Pot Four-Component Synthesis of 3,4-Dihydro-2-Pyridone Derivatives: Novel Urease Inhibitor Scaffold, Research in Pharmaceutical Sciences (2017)

Experts (# of related papers)

View all Related Experts

Mohammad Mahdavi (10)

Alireza Foroumadi (6)

Other Related Docs

4. A One-Pot, Three-Component, Solvent-Free Synthesis of Novel 6H-Chromeno[3’,4’:5,6]Pyrido[2,3-D]Pyrimidine-Triones Under Microwave Irradiation, Journal of Chemical Research (2018)

5. One-Pot Reaction of 3-Vinylchromones, Aromatic Aldehydes, and Ammonium Acetate: An Efficient Approach to Highly Functionalized 1,6-Dihydropyridine Derivatives, RSC Advances (2025)

6. One-Pot Four-Component Synthesis of Thieno[2,3-D]Pyrimidin-4-Amines Via Sequential Gewald/Cyclocondensation Reactions, Helvetica Chimica Acta (2015)

7. A Green and Efficient Synthesis of 2-Thioxoquinazolinone Derivatives in Water Using Potassium Thiocyanate, Journal of Sulfur Chemistry (2017)

8. Method for the Synthesis of Chromenopyrimidine-Fused Azoles by Copper-Catalyzed Intramolecular Hetero-Diels–Alder Reaction, Chemistry of Heterocyclic Compounds (2023)

9. Four-Component Heterocyclization Reaction for the One-Pot Synthesis of 2,4-Dichloro-Substituted Pyrano/Furo[2,3-D]Pyrimidines in an Environmentally Benign Procedure Mediated by Ceric Ammonium Nitrate in Phosphorus Ionic Liquid, Polycyclic Aromatic Compounds (2023)

10. An Efficient Approach to the Synthesis of Coumarin-Fused Dihydropyridinones, Heterocyclic Communications (2017)

11. Simple and Efficient Syntheses of Novel Benzo[4,5]Imidazo[1,2-A]Pyridine Derivatives, Tetrahedron Letters (2015)

12. Efficient One-Pot Synthesis of Novel 6′,9′-Dihydro-2H,7′H-Spiro[Pyrimidine-5,8′-[1,3]Dioxolo[4,5-F]Quinoline]-2,4,6(1H,3H)-Trione Derivatives Under Mild and “Green” Reaction Conditions, Journal of Heterocyclic Chemistry (2020)

13. An Efficient and Green Synthesis of New 6-Iodo- Pyrano[2,3-D] Pyrimidine-4-Ones Via a One-Pot Four-Component Reaction Followed by Iodocyclization in Water, Polycyclic Aromatic Compounds (2023)

14. Synthesis of Novel Dibenzylbutyrolactones As Dimethylmatairesinol Analogues, Journal of Heterocyclic Chemistry (2015)

15. A Comprehensive Review: Medicinal Applications and Diverse Synthetic Strategies of Pyrimidine-Based Compounds Leveraging Suzuki and Sonogashira Reactions, Monatshefte fur Chemie (2024)

16. A Convenient Method for the Synthesis of Chromeno[4,3-B]Pyridines Via Three-Component Reaction, Combinatorial Chemistry and High Throughput Screening (2018)

17. An Efficient Access to 2,3-Diarylimidazo[1,2-A]Pyridines Via Silver(I)-Catalyzed C-H Bond Functionalization, Monatshefte fur Chemie (2017)

18. Efficient Synthesis of Polyfunctionalized Pyrimidine Derivatives, Synlett (2016)

Style	Citing Format
MLA	Ghaedi A, et al.. "Facile Access to New Pyrido[2,3-D]Pyrimidine Derivatives." Molecular Diversity, vol. 23, no. 2, 2019, pp. 333-340.
APA	Ghaedi A, Bardajee GR, Mirshokrayi A, Mahdavi M, Akbarzadeh T (2019). Facile Access to New Pyrido[2,3-D]Pyrimidine Derivatives. Molecular Diversity, 23(2), 333-340.
Chicago	Ghaedi A, Bardajee GR, Mirshokrayi A, Mahdavi M, Akbarzadeh T. "Facile Access to New Pyrido[2,3-D]Pyrimidine Derivatives." Molecular Diversity 23, no. 2 (2019): 333-340.
Harvard	Ghaedi A et al. (2019) 'Facile Access to New Pyrido[2,3-D]Pyrimidine Derivatives', Molecular Diversity, 23(2), pp. 333-340.
Vancouver	Ghaedi A, Bardajee GR, Mirshokrayi A, Mahdavi M, Akbarzadeh T. Facile Access to New Pyrido[2,3-D]Pyrimidine Derivatives. Molecular Diversity. 2019;23(2):333-340.
BibTex	@article{ author = {Ghaedi A and Bardajee GR and Mirshokrayi A and Mahdavi M and Akbarzadeh T}, title = {Facile Access to New Pyrido[2,3-D]Pyrimidine Derivatives}, journal = {Molecular Diversity}, volume = {23}, number = {2}, pages = {333-340}, year = {2019} }
RIS	TY - JOUR AU - Ghaedi A AU - Bardajee GR AU - Mirshokrayi A AU - Mahdavi M AU - Akbarzadeh T TI - Facile Access to New Pyrido[2,3-D]Pyrimidine Derivatives JO - Molecular Diversity VL - 23 IS - 2 SP - 333 EP - 340 PY - 2019 ER -

Science Communicator Platform

Authors

Abstract