Covid-19 Virus May Have Neuroinvasive Potential and Cause Neurological Complications: A Perspective Review Publisher Pubmed



Sepehrinezhad A^{1, 2} ; Shahbazi A^{1, 3} ; Negah SS^{2, 4, 5}
Source: Journal of NeuroVirology Published:2020

Abstract

Coronavirus disease 2019 (COVID-19) was reported at the end of 2019 in China for the first time and has rapidly spread throughout the world as a pandemic. Since COVID-19 causes mild to severe acute respiratory syndrome, most studies in this field have only focused on different aspects of pathogenesis in the respiratory system. However, evidence suggests that COVID-19 may affect the central nervous system (CNS). Given the outbreak of COVID-19, it seems necessary to perform investigations on the possible neurological complications in patients who suffered from COVID-19. Here, we reviewed the evidence of the neuroinvasive potential of coronaviruses and discussed the possible pathogenic processes in CNS infection by COVID-19 to provide a precise insight for future studies. © 2020, Journal of NeuroVirology, Inc.