Risk Factors Affecting the Age at Onset in Adult Patients With Multiple Sclerosis

Risk Factors Affecting the Age at Onset in Adult Patients With Multiple Sclerosis Publisher Pubmed

Lapevandani MM ; Khodadadi S ; Naghitehrani KH ; Ayoubi S ; Eskandarieh S ; Sahraian MA

Source: BMC Neurology Published:2026

Abstract

Several factors can predispose patients to experience a sooner onset of multiple sclerosis (MS). In this study, we aimed to investigate the possible effect of environmental factors on the age at onset of adult-onset MS. Methods In this cross-sectional study, 6802 MS patients with age at onset after 18 years old and below 50 years old were included. Descriptive and regression analysis was applied to assess the correlation between age at onset and environmental factors. Results Chronic diseases and reproductive history were associated with a later onset, while smoking showed a complex relationship with onset timing. Conclusion Environmental factors can possibly alter the age at MS onset in adults. © The Author(s) 2026.

Style	Citing Format
MLA	Lapevandani MM, et al.. "Risk Factors Affecting the Age at Onset in Adult Patients With Multiple Sclerosis." BMC Neurology, vol. 26, no. 1, 2026, pp. -.
APA	Lapevandani MM, Khodadadi S, Naghitehrani KH, Ayoubi S, Eskandarieh S, Sahraian MA (2026). Risk Factors Affecting the Age at Onset in Adult Patients With Multiple Sclerosis. BMC Neurology, 26(1), -.
Chicago	Lapevandani MM, Khodadadi S, Naghitehrani KH, Ayoubi S, Eskandarieh S, Sahraian MA. "Risk Factors Affecting the Age at Onset in Adult Patients With Multiple Sclerosis." BMC Neurology 26, no. 1 (2026): -.
Harvard	Lapevandani MM et al. (2026) 'Risk Factors Affecting the Age at Onset in Adult Patients With Multiple Sclerosis', BMC Neurology, 26(1), pp. -.
Vancouver	Lapevandani MM, Khodadadi S, Naghitehrani KH, Ayoubi S, Eskandarieh S, Sahraian MA. Risk Factors Affecting the Age at Onset in Adult Patients With Multiple Sclerosis. BMC Neurology. 2026;26(1):-.
BibTex	@article{ author = {Lapevandani MM and Khodadadi S and Naghitehrani KH and Ayoubi S and Eskandarieh S and Sahraian MA}, title = {Risk Factors Affecting the Age at Onset in Adult Patients With Multiple Sclerosis}, journal = {BMC Neurology}, volume = {26}, number = {1}, pages = {-}, year = {2026} }
RIS	TY - JOUR AU - Lapevandani MM AU - Khodadadi S AU - Naghitehrani KH AU - Ayoubi S AU - Eskandarieh S AU - Sahraian MA TI - Risk Factors Affecting the Age at Onset in Adult Patients With Multiple Sclerosis JO - BMC Neurology VL - 26 IS - 1 SP - EP - PY - 2026 ER -

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