Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
Doppler Finding, Cardiovascular Function Assessment, and Fetuses’ Survival Following the Fetoscopic Laser in Twin-To-Twin Transfusion Syndrome Publisher



Bojnordi TE1 ; Eslamian L1 ; Marsoosi V1 ; Golbabaei A2 ; Vatan MS1 ; Shamshirsaz AA3 ; Eshraghi N4 ; Ghaemi M4
Authors

Source: Journal of Lasers in Medical Sciences Published:2023


Abstract

Introduction: This study aimed to evaluate the effectiveness of selective laser photocoagulation of communicating vessels (SLPCV) on cardiac function in twins with twin-to-twin transfusion syndrome (TTTS). Methods: This retrospective cohort study evaluated 178 women with twin pregnancies complicated with TTTS and scheduled for SLPCV between 16 and 26 weeks of gestation. The severity of TTTS was determined by Quintero staging and the severity of cardiovascular disorders by the CHOP (Children's Hospital of Philadelphia) score. Patient survival was evaluated through a one-month-after-birth follow-up of fetuses. Results: The study revealed significant improvements in Doppler indices in both donors and recipients after SLPCV. The CHOP score also significantly decreased after the intervention. One-month-after-birth survival rates were 55.1% in donors and 56.7% in recipients. Some Doppler indexes of fetuses before SLPCV could predict survival until one month after birth. Conclusion: The study suggests that SLPCV can improve cardiac function in fetuses with TTTS and that some Doppler indexes can predict survival outcomes. Additionally, the severity of TTTS can be a powerful indicator of the severity of cardiovascular complications. © (2023), (Laser Application in Medical Sciences Research Center). All Rights Reserved.
Other Related Docs
5. Intervention or Expectant Management for Stage I Twin-Twin Transfusion Syndrome, Best Practice and Research: Clinical Obstetrics and Gynaecology (2025)
14. Evaluation of Second-Trimester Maternal Serum Afp Value in the Detection of Congenital Heart Defects, Middle East Journal of Rehabilitation and Health Studies (2021)