Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
A Single Dose of Misoprostol for Reducing Hemorrhage During Myomectomy: A Randomized Clinical Trial Publisher Pubmed



Niroomand N1 ; Hajiha S1 ; Tabrizi NM1 ; Ghajarzadeh M2
Authors

Source: Archives of Gynecology and Obstetrics Published:2015


Abstract

Purpose: To evaluate the effect of vaginal misoprostol on intraoperative bleeding during myomectomy. Method: In this randomized clinical trial, 80 women with myomas were randomly assigned to receive 200 µg misoprostol or placebo (vitamin B6) 3 h before surgery. Blood loss during surgery, postoperative need for blood transfusion, and the hemoglobin level before surgery, and 6 and 12 h after surgery were assessed in two groups. Results: Mean age and the mean preoperative and postoperative Hb levels were not significantly different between the two groups. Mean duration of surgery and mean estimated blood loss were significantly higher in control group. Nine (22.5 %) patients in control group needed blood transfusion while there was no need blood transfusion in misoprostol group (p = 0.001). Conclusion: A single dose of vaginal misoprostol is effective in reducing hemorrhage during myomectomy. © 2015, Springer-Verlag Berlin Heidelberg.
Other Related Docs
4. Comparison of Two Dosing Regimens of Intravaginal Misoporostol for Second-Trimester Abortion, Iranian Journal of Obstetrics# Gynecology and Infertility (2018)
6. The Effect of Oxytocin Drip During Hysteroscopy on Operative Blood Loss and Fluid Overload, Journal of Obstetrics# Gynecology and Cancer Research (2020)
12. Desmopressin Effects on Bleeding During Functional Endoscopic Sinus Surgery on Patients With Chronic Rhinosinusitis, American Journal of Otolaryngology - Head and Neck Medicine and Surgery (2021)