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Macromolecular Biomarkers of Chronic Obstructive Pulmonary Disease in Exhaled Breath Condensate Publisher Pubmed



Kazeminasab S1, 2 ; Emamalizadeh B3 ; Jouyban A1, 4 ; Shoja MM5 ; Khoubnasabjafari M6, 7
Authors

Source: Biomarkers in Medicine Published:2020


Abstract

Biomarkers provide important diagnostic and prognostic information on heterogeneous diseases such as chronic obstructive pulmonary disease (COPD). However, finding a suitable specimen for clinical analysis of biomarkers for COPD is challenging. Exhaled breath condensate (EBC) sampling is noninvasive, rapid, cost-effective and easily repeatable. EBC sampling has also provided recent progress in the identification of biological macromolecules, such as lipids, proteins and DNA in EBC samples, which has increased its utility for clinical scientists. In this article, we review applications involving EBC sampling for the analysis of COPD biomarkers and discuss its future potential. © 2020 Future Medicine Ltd.
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