Updated S2 K Guidelines for the Management of Bullous Pemphigoid Initiated by the European Academy of Dermatology and Venereology (Eadv)

Updated S2 K Guidelines for the Management of Bullous Pemphigoid Initiated by the European Academy of Dermatology and Venereology (Eadv) Publisher Pubmed

Borradori L¹ ; Van Beek N² ; Feliciani C³ ; Tedbirt B⁴ ; Antiga E⁵ ; Bergman R^{6, 7} ; Bockle BC⁸ ; Caproni M⁹ ; Caux F¹⁰ ; Chandran NS¹¹ ; Cianchini G¹² ; Daneshpazhooh M¹³ ; De D¹⁴ ; Didona D¹⁵ Show All Authors

Borradori L¹
Van Beek N²
Feliciani C³
Tedbirt B⁴
Antiga E⁵
Bergman R^{6, 7}
Bockle BC⁸
Caproni M⁹
Caux F¹⁰
Chandran NS¹¹
Cianchini G¹²
Daneshpazhooh M¹³
De D¹⁴
Didona D¹⁵
Di Zenzo GM¹⁶
Dmochowski M¹⁷
Drenovska K¹⁸
Ehrchen J¹⁹
Goebeler M²⁰
Groves R^{21, 22}
Gunther C²³
Horvath B²⁴
Hertl M¹⁵
Hofmann S²⁵
Ioannides D²⁶
Itzlingermonshi B^{27, 28}
Jedlickova J^{29, 30}
Kowalewski C³¹
Kridin K³²
Lim YL³³
Marinovic B³⁴
Marzano AV^{34, 35}
Mascaro JM³⁶
Meijer JM²⁴
Murrell D³⁷
Patsatsi K³⁸
Pincelli C³⁹
Prost C¹⁰
Rappersberger K^{27, 28, 40}
Sardy M^{41, 42}
Setterfield J⁴³
Shahid M⁴⁴
Sprecher E⁴⁵
Tasanen K⁴⁶
Uzun S⁴⁷
Vassileva S⁴⁴
Vestergaard K⁴⁸
Vorobyev A^{2, 49}
Vujic I^{27, 28}
Wang G⁵⁰
Wozniak K³²
Yayli S⁵¹
Zambruno G⁵²
Zillikens D^{2, 49}
Schmidt E^{2, 53}
Joly P⁴

Source: Journal of the European Academy of Dermatology and Venereology Published:2022

Abstract

Background: Bullous pemphigoid (BP) is the most common autoimmune subepidermal blistering disease of the skin and mucous membranes. This disease typically affects the elderly and presents with itch and localized or, most frequently, generalized bullous lesions. A subset of patients only develops excoriations, prurigo-like lesions, and eczematous and/or urticarial erythematous lesions. The disease, which is significantly associated with neurological disorders, has high morbidity and severely impacts the quality of life. Objectives and methodology: The Autoimmune blistering diseases Task Force of the European Academy of Dermatology and Venereology sought to update the guidelines for the management of BP based on new clinical information, and new evidence on diagnostic tools and interventions. The recommendations are either evidence-based or rely on expert opinion. The degree of consent among all task force members was included. Results: Treatment depends on the severity of BP and patients' comorbidities. High-potency topical corticosteroids are recommended as the mainstay of treatment whenever possible. Oral prednisone at a dose of 0.5 mg/kg/day is a recommended alternative. In case of contraindications or resistance to corticosteroids, immunosuppressive therapies, such as methotrexate, azathioprine, mycophenolate mofetil or mycophenolate acid, may be recommended. The use of doxycycline and dapsone is controversial. They may be recommended, in particular, in patients with contraindications to oral corticosteroids. B-cell-depleting therapy and intravenous immunoglobulins may be considered in treatment-resistant cases. Omalizumab and dupilumab have recently shown promising results. The final version of the guideline was consented to by several patient organizations. Conclusions: The guidelines for the management of BP were updated. They summarize evidence- and expert-based recommendations useful in clinical practice. © 2022 The Authors. Journal of the European Academy of Dermatology and Venereology published by John Wiley & Sons Ltd on behalf of European Academy of Dermatology and Venereology.

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Style	Citing Format
MLA	Borradori L, et al.. "Updated S2 K Guidelines for the Management of Bullous Pemphigoid Initiated by the European Academy of Dermatology and Venereology (Eadv)." Journal of the European Academy of Dermatology and Venereology, vol. 36, no. 10, 2022, pp. 1689-1704.
APA	Borradori L, Van Beek N, Feliciani C, Tedbirt B, Antiga E, Bergman R, Bockle BC, Caproni M, Caux F, Chandran NS, Cianchini G, Daneshpazhooh M, De D, Didona D, Di Zenzo GM, Dmochowski M, Drenovska K, Ehrchen J, Goebeler M, ... Joly P (2022). Updated S2 K Guidelines for the Management of Bullous Pemphigoid Initiated by the European Academy of Dermatology and Venereology (Eadv). Journal of the European Academy of Dermatology and Venereology, 36(10), 1689-1704.
Chicago	Borradori L, Van Beek N, Feliciani C, Tedbirt B, Antiga E, Bergman R, Bockle BC, et al.. "Updated S2 K Guidelines for the Management of Bullous Pemphigoid Initiated by the European Academy of Dermatology and Venereology (Eadv)." Journal of the European Academy of Dermatology and Venereology 36, no. 10 (2022): 1689-1704.
Harvard	Borradori L et al. (2022) 'Updated S2 K Guidelines for the Management of Bullous Pemphigoid Initiated by the European Academy of Dermatology and Venereology (Eadv)', Journal of the European Academy of Dermatology and Venereology, 36(10), pp. 1689-1704.
Vancouver	Borradori L, Van Beek N, Feliciani C, Tedbirt B, Antiga E, Bergman R, et al.. Updated S2 K Guidelines for the Management of Bullous Pemphigoid Initiated by the European Academy of Dermatology and Venereology (Eadv). Journal of the European Academy of Dermatology and Venereology. 2022;36(10):1689-1704.
BibTex	@article{ author = {Borradori L and Van Beek N and Feliciani C and Tedbirt B and Antiga E and Bergman R and Bockle BC and Caproni M and Caux F and Chandran NS and Cianchini G and Daneshpazhooh M and De D and Didona D and Di Zenzo GM and Dmochowski M and Drenovska K and Ehrchen J and Goebeler M and Groves R and Gunther C and Horvath B and Hertl M and Hofmann S and Ioannides D and Itzlingermonshi B and Jedlickova J and Kowalewski C and Kridin K and Lim YL and Marinovic B and Marzano AV and Mascaro JM and Meijer JM and Murrell D and Patsatsi K and Pincelli C and Prost C and Rappersberger K and Sardy M and Setterfield J and Shahid M and Sprecher E and Tasanen K and Uzun S and Vassileva S and Vestergaard K and Vorobyev A and Vujic I and Wang G and Wozniak K and Yayli S and Zambruno G and Zillikens D and Schmidt E and Joly P}, title = {Updated S2 K Guidelines for the Management of Bullous Pemphigoid Initiated by the European Academy of Dermatology and Venereology (Eadv)}, journal = {Journal of the European Academy of Dermatology and Venereology}, volume = {36}, number = {10}, pages = {1689-1704}, year = {2022} }
RIS	TY - JOUR AU - Borradori L AU - Van Beek N AU - Feliciani C AU - Tedbirt B AU - Antiga E AU - Bergman R AU - Bockle BC AU - Caproni M AU - Caux F AU - Chandran NS AU - Cianchini G AU - Daneshpazhooh M AU - De D AU - Didona D AU - Di Zenzo GM AU - Dmochowski M AU - Drenovska K AU - Ehrchen J AU - Goebeler M AU - Groves R AU - Gunther C AU - Horvath B AU - Hertl M AU - Hofmann S AU - Ioannides D AU - Itzlingermonshi B AU - Jedlickova J AU - Kowalewski C AU - Kridin K AU - Lim YL AU - Marinovic B AU - Marzano AV AU - Mascaro JM AU - Meijer JM AU - Murrell D AU - Patsatsi K AU - Pincelli C AU - Prost C AU - Rappersberger K AU - Sardy M AU - Setterfield J AU - Shahid M AU - Sprecher E AU - Tasanen K AU - Uzun S AU - Vassileva S AU - Vestergaard K AU - Vorobyev A AU - Vujic I AU - Wang G AU - Wozniak K AU - Yayli S AU - Zambruno G AU - Zillikens D AU - Schmidt E AU - Joly P TI - Updated S2 K Guidelines for the Management of Bullous Pemphigoid Initiated by the European Academy of Dermatology and Venereology (Eadv) JO - Journal of the European Academy of Dermatology and Venereology VL - 36 IS - 10 SP - 1689 EP - 1704 PY - 2022 ER -

Style

Citing Format

MLA

Borradori L, et al.. "Updated S2 K Guidelines for the Management of Bullous Pemphigoid Initiated by the European Academy of Dermatology and Venereology (Eadv)." Journal of the European Academy of Dermatology and Venereology, vol. 36, no. 10, 2022, pp. 1689-1704.

APA

Borradori L, Van Beek N, Feliciani C, Tedbirt B, Antiga E, Bergman R, Bockle BC, Caproni M, Caux F, Chandran NS, Cianchini G, Daneshpazhooh M, De D, Didona D, Di Zenzo GM, Dmochowski M, Drenovska K, Ehrchen J, Goebeler M, ... Joly P (2022). Updated S2 K Guidelines for the Management of Bullous Pemphigoid Initiated by the European Academy of Dermatology and Venereology (Eadv). Journal of the European Academy of Dermatology and Venereology, 36(10), 1689-1704.

Chicago

Borradori L, Van Beek N, Feliciani C, Tedbirt B, Antiga E, Bergman R, Bockle BC, et al.. "Updated S2 K Guidelines for the Management of Bullous Pemphigoid Initiated by the European Academy of Dermatology and Venereology (Eadv)." Journal of the European Academy of Dermatology and Venereology 36, no. 10 (2022): 1689-1704.

Harvard

Borradori L et al. (2022) 'Updated S2 K Guidelines for the Management of Bullous Pemphigoid Initiated by the European Academy of Dermatology and Venereology (Eadv)', Journal of the European Academy of Dermatology and Venereology, 36(10), pp. 1689-1704.

Vancouver

Borradori L, Van Beek N, Feliciani C, Tedbirt B, Antiga E, Bergman R, et al.. Updated S2 K Guidelines for the Management of Bullous Pemphigoid Initiated by the European Academy of Dermatology and Venereology (Eadv). Journal of the European Academy of Dermatology and Venereology. 2022;36(10):1689-1704.

BibTex

@article{ author = {Borradori L and Van Beek N and Feliciani C and Tedbirt B and Antiga E and Bergman R and Bockle BC and Caproni M and Caux F and Chandran NS and Cianchini G and Daneshpazhooh M and De D and Didona D and Di Zenzo GM and Dmochowski M and Drenovska K and Ehrchen J and Goebeler M and Groves R and Gunther C and Horvath B and Hertl M and Hofmann S and Ioannides D and Itzlingermonshi B and Jedlickova J and Kowalewski C and Kridin K and Lim YL and Marinovic B and Marzano AV and Mascaro JM and Meijer JM and Murrell D and Patsatsi K and Pincelli C and Prost C and Rappersberger K and Sardy M and Setterfield J and Shahid M and Sprecher E and Tasanen K and Uzun S and Vassileva S and Vestergaard K and Vorobyev A and Vujic I and Wang G and Wozniak K and Yayli S and Zambruno G and Zillikens D and Schmidt E and Joly P}, title = {Updated S2 K Guidelines for the Management of Bullous Pemphigoid Initiated by the European Academy of Dermatology and Venereology (Eadv)}, journal = {Journal of the European Academy of Dermatology and Venereology}, volume = {36}, number = {10}, pages = {1689-1704}, year = {2022} }

RIS

TY - JOUR
AU - Borradori L
AU - Van Beek N
AU - Feliciani C
AU - Tedbirt B
AU - Antiga E
AU - Bergman R
AU - Bockle BC
AU - Caproni M
AU - Caux F
AU - Chandran NS
AU - Cianchini G
AU - Daneshpazhooh M
AU - De D
AU - Didona D
AU - Di Zenzo GM
AU - Dmochowski M
AU - Drenovska K
AU - Ehrchen J
AU - Goebeler M
AU - Groves R
AU - Gunther C
AU - Horvath B
AU - Hertl M
AU - Hofmann S
AU - Ioannides D
AU - Itzlingermonshi B
AU - Jedlickova J
AU - Kowalewski C
AU - Kridin K
AU - Lim YL
AU - Marinovic B
AU - Marzano AV
AU - Mascaro JM
AU - Meijer JM
AU - Murrell D
AU - Patsatsi K
AU - Pincelli C
AU - Prost C
AU - Rappersberger K
AU - Sardy M
AU - Setterfield J
AU - Shahid M
AU - Sprecher E
AU - Tasanen K
AU - Uzun S
AU - Vassileva S
AU - Vestergaard K
AU - Vorobyev A
AU - Vujic I
AU - Wang G
AU - Wozniak K
AU - Yayli S
AU - Zambruno G
AU - Zillikens D
AU - Schmidt E
AU - Joly P
TI - Updated S2 K Guidelines for the Management of Bullous Pemphigoid Initiated by the European Academy of Dermatology and Venereology (Eadv)
JO - Journal of the European Academy of Dermatology and Venereology
VL - 36
IS - 10
SP - 1689
EP - 1704
PY - 2022
ER -

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