Comparison of the Frequency of Dumping Syndrome Following Gastric Bypass and Sleeve Gastrectomy in Patients With Morbid Obesity; [مقایسه فراوانی سندرم دامپینگ در دو روش جراحی گاستریک بای پاس و اسلیو گاستر کتومی در بیماران مبتلا به چاقی مرضی]



Sharafi Y ; Talebpour M ; Najari K
Source: Tehran University Medical Journal Published:2025

Abstract

Background: Dumping syndrome is a common complication after bariatric surgery and can adversely affect patients’ quality of life, particularly in those with diabetes. Although gastric bypass has traditionally been associated with a higher risk of dumping syndrome, evidence comparing its frequency with sleeve gastrectomy remains inconclusive. This study aimed to compare the frequency of dumping syndrome following these two procedures in patients with morbid obesity. Methods: This prospective cohort study was conducted from April 2021 to July 2022 at Sina Hospital in Tehran. A total of 90 patients with morbid obesity who met the indications for bariatric surgery were not randomly assigned to two treatment groups: gastric bypass (n = 45) and sleeve gastrectomy (n = 45). Baseline assessments included medical history, physical examination, review of medical records, and necessary specialist consultations (including endocrinology and cardiology). All patients’ data were recorded in the Sina Bariatric Surgery Registry Database. Following surgery, patients received standard postoperative care and were evaluated for symptoms of dumping syndrome at one and three months postoperatively using the validated Sigstad questionnaire. Statistical analyses were performed using SPSS software. Results: The results showed no statistically significant differences between the two groups in terms of age group, gender, excess weight, preoperative BMI, final BMI, and history of diabetes prior to surgery (P-value > 0.05). The final weight was significantly higher in the sleeve gastrectomy group (P-value = 0.033). There were no significant differences in the frequency of early and late dumping syndrome related to the consumption of sweets and other foods between the two groups at the first and third postoperative months (P-value > 0.05). Early dumping syndrome following the consumption of sweets and bread was significantly more frequent among diabetic patients (P-value = 0.037 and P-value = 0.045, respectively). Conclusion: The prevalence of dumping syndrome was similar in both sleeve and bypass groups. Weight loss over time was significant (P < 0.001) and did not differ between groups (P = 0.211). The syndrome was significantly more common in diabetic patients, highlighting the importance of careful postoperative care and dietary guidance. Copyright © 2025 Sharafi et al. Published by Tehran University of Medical Sciences. This work is licensed under a Creative Commons Attribution-Non-Commercial 4.0 International license (https://creativecommons.org/licenses/by-nc/4.0/). Non-commercial uses of thework are permitted, provided the original work is properly cited.