Telovelar Vs. Transvermian Approach for the Fourth Ventricle Tumors: A Systematic Review and Meta-Analysis Publisher Pubmed



Hanaei S^{1, 2} ; Maroufi SF^{1, 3} ; Sadeghmousavi S^{2, 3} ; Nejati A¹ ; Paeinmahalli A^{1, 2} ; Ohadi MAD¹ ; Teo C^{4, 5, 6, 7}
Source: Clinical Neurology and Neurosurgery Published:2024

Abstract

Background: Tumors in the fourth ventricle can be critical due to the small size of the fourth ventricle, which causes symptoms to be detected even in the presence of lesser mass effects. A proper surgical approach to the fourth ventricle poses challenges due to its deep location and proximity to vital compartments within the brainstem. The two commonly used approaches to these tumors are the transvermian and telovelar approaches. Methods: A comprehensive systematic study was conducted based on a literature search of the databases. All case controls, cohorts, and case series including patients with fourth ventricle tumors, who were operated on with either telovelar or transvermian approaches were considered eligible. The evaluated outcomes were comparative postoperative complications of the telovelar vs. transvermian approach. After screening and data extraction, a meta-analysis was performed whenever adequate quantitative data were available. Results: Seven studies with a total number of 848 patients, discussed both telovelar and transvermian approaches, with comparative reporting of outcomes in each group. Postoperative outcomes including cranial nerve deficit, mutism, diplopia, CSF leak, need for CSF diversion, and postoperative gait disturbance were not significantly different between telovelar and transvermian approaches. Conclusion: Postoperative complications were not significantly different between telovelar and transvermian approaches. Moreover, it could be proposed that such complications would be more likely to be a multifactorial matter concerning the patient's clinical condition, tumor characteristics, and surgeon's experience, rather than the surgical approach alone. © 2024 Elsevier B.V.