Myocardial Cell Signaling During the Transition to Heart Failure: Cellular Signaling and Therapeutic Approaches

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Myocardial Cell Signaling During the Transition to Heart Failure: Cellular Signaling and Therapeutic Approaches Publisher Pubmed

Zeglinski MR¹ ; Moghadam AR² ; Ande SR³ ; Sheikholeslami K^{2, 14} ; Mokarram P⁴ ; Sepehri Z^{2, 15} ; Rokni H² ; Mohtaram NK^{5, 16} ; Poorebrahim M⁶ ; Masoom A⁷ ; Toback M⁸ ; Sareen N¹ ; Saravanan S^{1, 13} ; Jassal DS¹ Show All Authors

Zeglinski MR¹
Moghadam AR²
Ande SR³
Sheikholeslami K^{2, 14}
Mokarram P⁴
Sepehri Z^{2, 15}
Rokni H²
Mohtaram NK^{5, 16}
Poorebrahim M⁶
Masoom A⁷
Toback M⁸
Sareen N¹
Saravanan S^{1, 13}
Jassal DS¹
Hashemi M⁹
Marzban H²
Schaafsma D²
Singal P¹
Wigle JT¹
Czubryt MP¹
Akbari M⁵
Dixon IMC¹
Ghavami S^{2, 11, 12}
Gordon JW^{2, 10}
Dhingra S¹

Source: Comprehensive Physiology Published:2019

Abstract

Cardiovascular disease leading to heart failure (HF) remains a leading cause of morbidity and mortality worldwide. Improved pharmacological and interventional coronary procedures have led to improved outcomes following acute myocardial infarction. This success has translated into an unforeseen increased incidence in HF. This review summarizes the signaling pathways implicated in the transition to HF following cardiac injury. In addition, we provide an update on cell death signaling and discuss recent advances in cardiac fibrosis as an independent event leading to HF. Finally, we discuss cell-based therapies and their possible use to avert the deteriorating nature of HF. © 2019 American Physiological Society.

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Style	Citing Format
MLA	Zeglinski MR, et al.. "Myocardial Cell Signaling During the Transition to Heart Failure: Cellular Signaling and Therapeutic Approaches." Comprehensive Physiology, vol. 9, no. 1, 2019, pp. 75-125.
APA	Zeglinski MR, Moghadam AR, Ande SR, Sheikholeslami K, Mokarram P, Sepehri Z, Rokni H, Mohtaram NK, Poorebrahim M, Masoom A, Toback M, Sareen N, Saravanan S, Jassal DS, Hashemi M, Marzban H, Schaafsma D, Singal P, Wigle JT, ... Dhingra S (2019). Myocardial Cell Signaling During the Transition to Heart Failure: Cellular Signaling and Therapeutic Approaches. Comprehensive Physiology, 9(1), 75-125.
Chicago	Zeglinski MR, Moghadam AR, Ande SR, Sheikholeslami K, Mokarram P, Sepehri Z, Rokni H, et al.. "Myocardial Cell Signaling During the Transition to Heart Failure: Cellular Signaling and Therapeutic Approaches." Comprehensive Physiology 9, no. 1 (2019): 75-125.
Harvard	Zeglinski MR et al. (2019) 'Myocardial Cell Signaling During the Transition to Heart Failure: Cellular Signaling and Therapeutic Approaches', Comprehensive Physiology, 9(1), pp. 75-125.
Vancouver	Zeglinski MR, Moghadam AR, Ande SR, Sheikholeslami K, Mokarram P, Sepehri Z, et al.. Myocardial Cell Signaling During the Transition to Heart Failure: Cellular Signaling and Therapeutic Approaches. Comprehensive Physiology. 2019;9(1):75-125.
BibTex	@article{ author = {Zeglinski MR and Moghadam AR and Ande SR and Sheikholeslami K and Mokarram P and Sepehri Z and Rokni H and Mohtaram NK and Poorebrahim M and Masoom A and Toback M and Sareen N and Saravanan S and Jassal DS and Hashemi M and Marzban H and Schaafsma D and Singal P and Wigle JT and Czubryt MP and Akbari M and Dixon IMC and Ghavami S and Gordon JW and Dhingra S}, title = {Myocardial Cell Signaling During the Transition to Heart Failure: Cellular Signaling and Therapeutic Approaches}, journal = {Comprehensive Physiology}, volume = {9}, number = {1}, pages = {75-125}, year = {2019} }
RIS	TY - JOUR AU - Zeglinski MR AU - Moghadam AR AU - Ande SR AU - Sheikholeslami K AU - Mokarram P AU - Sepehri Z AU - Rokni H AU - Mohtaram NK AU - Poorebrahim M AU - Masoom A AU - Toback M AU - Sareen N AU - Saravanan S AU - Jassal DS AU - Hashemi M AU - Marzban H AU - Schaafsma D AU - Singal P AU - Wigle JT AU - Czubryt MP AU - Akbari M AU - Dixon IMC AU - Ghavami S AU - Gordon JW AU - Dhingra S TI - Myocardial Cell Signaling During the Transition to Heart Failure: Cellular Signaling and Therapeutic Approaches JO - Comprehensive Physiology VL - 9 IS - 1 SP - 75 EP - 125 PY - 2019 ER -