Tehran University of Medical Sciences

Science Communicator Platform

Share By
Potential Roles of Lncrna-Xist/Mirnas/Mrnas in Human Cancer Cells Publisher Pubmed



Farzaneh M1 ; Nasrolahi A2 ; Ghaedrahmati F3 ; Masoodi T4 ; Najafi S5 ; Sheykhisabzehpoush M6 ; Dari MAG7 ; Radoszkiewicz K8 ; Uddin S9 ; Azizidoost S10 ; Khoshnam SE11
Authors

Source: Clinical and Translational Oncology Published:2023


Abstract

Long non-coding RNAs (lncRNAs) are non-coding RNAs that contain more than 200 nucleotides but do not code for proteins. In tumorigenesis, lncRNAs can have both oncogenic and tumor-suppressive properties. X inactive-specific transcript (XIST) is a known lncRNA that has been implicated in X chromosome silencing in female cells. Dysregulation of XIST is associated with an increased risk of various cancers. Therefore, XIST can be a beneficial prognostic biomarker for human malignancies. In this review, we attempt to summarize the emerging roles of XIST in human cancers. © 2023, The Author(s), under exclusive licence to Federacion de Sociedades Espanolas de Oncologia (FESEO).
Related Docs
View other Related Docs
1. Down-Regulation of a Panel of Immune-Related Lncrnas in Breast Cancer, Pathology Research and Practice (2021)
2. Long Noncoding Rnas and Exosomal Lncrnas: Classification, and Mechanisms in Breast Cancer Metastasis and Drug Resistance, Oncogene (2020)
3. Expression Analysis of a Panel of Long Non-Coding Rnas (Lncrnas) Revealed Their Potential As Diagnostic Biomarkers in Bladder Cancer, Genomics (2020)
Experts (# of related papers)
View all Related Experts
Hamid Reza Mirzaei (2)
Zahra Azizi Varzaneh (1)
Other Related Docs
4. Long Non-Coding Rnas: Diverse Roles in Various Disorders, Human Antibodies (2019)
5. Expression Analysis of Four Long Noncoding Rnas in Breast Cancer, Tumor Biology (2016)
6. Long Non-Coding Rnas As Epigenetic Regulators in Cancer, Current Pharmaceutical Design (2019)
7. Crosstalk Between Lncrnas in the Apoptotic Pathway and Therapeutic Targets in Cancer, Cytokine and Growth Factor Reviews (2022)
8. The Interplay Between Lncrnas–Micrornas Network Dysregulation and Cellular Hallmarks of Thyroid Cancer, Cancers (2025)
9. Long Non-Coding Rna Signatures in Lymphopoiesis and Lymphoid Malignancies, Non-coding RNA (2023)
10. Modulation of Long Non-Coding Rnas and Micrornas by Quercetin As a Potential Therapeutical Approach in Cancer: A Comprehensive Review, Current Medicinal Chemistry (2025)
11. Role of Non-Coding Rnas and Exosomal Non-Coding Rnas in Retinoblastoma Progression, Frontiers in Cell and Developmental Biology (2022)
12. The Role of Curcumin in Modulating Circular Rnas and Long Non-Coding Rnas in Cancer, Clinical and Translational Oncology (2025)
13. Long Non-Coding Rnas in Diagnosis, Treatment, Prognosis, and Progression of Glioma: A State-Of-The-Art Review, Frontiers in Oncology (2021)
14. Autophagy and Gastrointestinal Cancers: The Behind the Scenes Role of Long Non-Coding Rnas in Initiation, Progression, and Treatment Resistance, Cancer Gene Therapy (2021)
15. Role of Non-Coding Rnas As New Therapeutic Targets in Regulating the Emt and Apoptosis in Metastatic Gastric and Colorectal Cancers, Cell Cycle (2023)
16. Long Non-Coding Rnas (Lncrnas); Roles in Tumorigenesis and Potentials As Biomarkers in Cancer Diagnosis, Experimental Cell Research (2022)
17. Role of Non-Coding Rnas in Neuroblastoma, Cancer Gene Therapy (2023)
18. Epigenetic Regulation in Myocardial Infarction: Non-Coding Rnas and Exosomal Non-Coding Rnas, Frontiers in Cardiovascular Medicine (2022)
19. A Systematic Review of Long Non-Coding Rnas With a Potential Role in Breast Cancer, Mutation Research - Reviews in Mutation Research (2021)
20. Innovative Targets of the Lncrna-Mir-Mrna Network in Response to Low-Dose Aspirin in Breast Cancer Patients, Scientific Reports (2022)