Development of Novel Low-Cost Readout Electronics for Large Field-Of-View Gamma Camera Detectors Publisher Pubmed

Summary: Gamma imaging upgrade? Study develops large FOV detector with PMT readout—8.7% energy res, 3.9mm spatial. Research suggests cost-effective quality. Scan smarter? #NuclearMedicine #GammaCamera

Radnia A¹ ; Alikhani A¹ ; Teimourian B¹ ; Nejad MY¹ ; Farahani MH¹ ; Pashaei F² ; Rahmim A^{4, 5} ; Zaidi H^{6, 7, 8, 9} ; Ay MR^{1, 3}
Source: Physica Medica Published:2024

Abstract

Purpose: Large scintillation crystals-based gamma cameras play a crucial role in nuclear medicine imaging. In this study, a large field-of-view (FOV) gamma detector consisting of 48 square PMTs developed using a new readout electronics, reducing 48 (6 × 8) analog signals to 14 (6 + 8) analog sums of each row and column, with reduced complexity and cost while preserving image quality. Methods: All 14 analog signals were converted to digital signals using AD9257 high-speed analog to digital (ADC) converters driven by the SPARTAN-6 family of field-programmable gate arrays (FPGA) in order to calculate the signal integrals. The positioning algorithm was based on the digital correlated signal enhancement (CSE) algorithm implemented in the acquisition software. The performance characteristics of the developed gamma camera were measured using the NEMA NU 1-2018 standards. Results: The measured energy resolution of the developed detector was 8.7 % at 140 keV, with an intrinsic spatial resolution of 3.9 mm. The uniformity was within 0.6 %, while the linearity was within 0.1 %. Conclusion: The performance evaluation demonstrated that the developed detector has suitable specifications for high-end nuclear medicine imaging. © 2024 Associazione Italiana di Fisica Medica e Sanitaria