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Serum Vitamin D Concentration and Anthropometric Indicators of Adiposity in Adults Without or With Low Dose Statin Users: A Cross-Sectional Study Publisher Pubmed



Ashraf H1 ; Maghbouli N2 ; Abolhasani M1 ; Zandi N3 ; Nematizadeh M3 ; Omidi N4 ; Davoodi G1 ; Boroumand MA1 ; Ali JH5
Authors

Source: Journal of Health, Population and Nutrition Published:2024


Abstract

Background: This study sought to determine the accuracy of several anthropometric parameters in association with serum Vit. D concentrations and to compare the novel indices with the conventional ones. Methods: A total of 947 individuals referred to the cardiology clinic who have not used statin or take low-dose statin were evaluated through a cross-sectional study. Data on demographic information, anthropometric indices, and biochemical measurements were gathered using a checklist. Both the multivariable regression modeling and the area under the receiver-operating characteristic (ROC) were employed for the analysis. Results: Considering novel indices, BRI (Body Roundness Index) showed the most powerful correlation with serum Vit. D levels among both genders. Among conventional ancient indices, WC (Waist Circumference) had the strongest association in both men and women groups. Based on the confounding factors-adjusted model, the highest odds ratio (OR) for the presence of Vit. D deficiency belonged to WHtR (Waist to Height Ratio) in women (OR, 0.347 (0.171–0.704), P = 0.003). None of the indices predicted Vit. D deficiency significantly among men. A Vit. D concentration of 4.55 ng/ml was found as a cutoff based on the metabolic syndrome status. Conclusion: The most powerful association with serum Vit. D levels were detected for BRI in both genders among newly developed indices. In addition, WHtR predicted Vit. D deficiency independent of confounding factors among women. © The Author(s) 2024.
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