Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
Scleromyxedema in an Adult Following Sinopharm Bbibp-Corv Vaccination: An Extremely Rare Phenomenon Publisher



Parsaei A1 ; Rezaei SS2 ; Rahmani A3 ; Masoumi M2 ; Dehghanbanadaki H4 ; Norouzi S2 ; Riyahi MM2 ; Tabaraii R2 ; Montazeri SMH5
Authors

Source: Journal of Scleroderma and Related Disorders Published:2023


Abstract

Introduction: The Sinopharm BBIBP-CorV vaccine produces a variety of cutaneous adverse effects. Scleromyxedema is a mucinous connective tissue disorder that causes skin thickness and sclerodermoid changes. According to our findings, this is the first case of scleromyxedema induced by the Sinopharm immunization. Case description: We discuss the case of a 75-year-old woman who acquired progressive thickening of the skin in her limbs and trunk after getting the Sinopharm vaccination. Examination, laboratory testing, and a biopsy were used to verify scleromyxedema diagnosis. Intravenous immunoglobulins, mycophenolate mofetil, and prednisolone were used in the treatment of the patient. The outcomes from the 4-month follow-up were reassuring. Conclusion: This study emphasizes the need of considering scleromyxedema as a connective tissue pathology in patients who have recently received Sinopharm vaccine and have similar cutaneous signs. © The Author(s) 2022.
Other Related Docs
10. Ophthalmic Side Effects of Covid-19 Vaccines, Expert Review of Ophthalmology (2022)
15. A Rare Case of Tumoral Scleromyxedema, Indian Journal of Dermatology (2020)